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Genetic engineering

Short-term succinic acid treatment mitigates cerebellar mitochondrial OXPHOS dysfunction, neurodegeneration and ataxia in a Purkinje-specific spinocerebellar ataxia type 1 (SCA1) mouse model

Austin Ferro, Emily Carbone, [ ... ], Sarita Lagalwar

Isoflurane Exposure during Mid-Adulthood Attenuates Age-Related Spatial Memory Impairment in APP/PS1 Transgenic Mice

Diansan Su, Yanxing Zhao, [ ... ], Xiangrui Wang

The Adaptor Protein Myd88 Is a Key Signaling Molecule in the Pathogenesis of Irinotecan-Induced Intestinal Mucositis

Deysi V. T. Wong, Roberto C. P. Lima-Júnior, [ ... ], Ronaldo A. Ribeiro

Transcriptome profiling of transgenic potato plants provides insights into variability caused by plant transformation

Dae Kwan Ko, Satya Swathi Nadakuduti, David S. Douches, C. Robin Buell

Overexpression of Two PsnAP1 Genes from Populus simonii × P. nigra Causes Early Flowering in Transgenic Tobacco and Arabidopsis

Tangchun Zheng, Shuang Li, [ ... ], Guan-Zheng Qu

Myocardial Injection of Apelin-Overexpressing Bone Marrow Cells Improves Cardiac Repair via Upregulation of Sirt3 after Myocardial Infarction

Lanfang Li, Heng Zeng, [ ... ], Jian-Xiong Chen

Mulberry Transcription Factor MnDREB4A Confers Tolerance to Multiple Abiotic Stresses in Transgenic Tobacco

Xue-Qin Liu, Chang-Ying Liu, [ ... ], Ai-Chun Zhao

StreptInCor: A Candidate Vaccine Epitope against S. pyogenes Infections Induces Protection in Outbred Mice

Edilberto Postol, Raquel Alencar, [ ... ], Luiza Guilherme

Conditional Tek Promoter-Driven Deletion of Arginyltransferase in the Germ Line Causes Defects in Gametogenesis and Early Embryonic Lethality in Mice

Nicolae Adrian Leu, Satoshi Kurosaka, Anna Kashina

Neural-Specific Deletion of Htra2 Causes Cerebellar Neurodegeneration and Defective Processing of Mitochondrial OPA1

Victoria L. Patterson, Alfred J. Zullo, [ ... ], Josephine Hoh

EHD1 Functions in Endosomal Recycling and Confers Salt Tolerance

Maya Bar, Meirav Leibman, [ ... ], Adi Avni

Activation of PyMT in β Cells Induces Irreversible Hyperplasia, but Oncogene-Dependent Acinar Cell Carcinomas When Activated in Pancreatic Progenitors

Yi-Chieh Nancy Du, David S. Klimstra, Harold Varmus

Macrophage Inhibitory Cytokine-1 (MIC-1/GDF15) Gene Deletion Promotes Cancer Growth in TRAMP Prostate Cancer Prone Mice

Yasmin Husaini, Glen P. Lockwood, [ ... ], Samuel N. Breit

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