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Genetic engineering

Deletion of SM22α disrupts the structure and function of caveolae and T-tubules in cardiomyocytes, contributing to heart failure

Jun Wu, Wei Wang, Yaomeng Huang, Haochen Wu, Jiabin Wang, Mei Han

published 18 Jul 2022

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Sex-, age-, and organ-dependent improvement of bile acid hydrophobicity by ursodeoxycholic acid treatment: A study using a mouse model with human-like bile acid composition

Hajime Ueda, Akira Honda, Teruo Miyazaki, Yukio Morishita, Takeshi Hirayama, Junichi Iwamoto, Nobuhiro Nakamoto, Tadashi Ikegami

published 12 Jul 2022

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A precise gene delivery approach for human induced pluripotent stem cells using Cas9 RNP complex and recombinant AAV6 donor vectors

Koollawat Chupradit, Nontaphat Thongsin, Chatchai Tayapiwatana, Methichit Wattanapanitch

published 07 Jul 2022

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Mitochondrial dysfunction is associated with lipid metabolism disorder and upregulation of angiotensin-converting enzyme 2

Qian Zhao, Xiaoshan Zhou, Raoul Kuiper, Sophie Curbo, Anna Karlsson

published 29 Jun 2022

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Evaluation of transgenic chickpea harboring codon-modified Vip3Aa against gram pod borer (Helicoverpa armigera H.)

Prateek Singh, Sujayanand G. K., Shallu Thakur, Meenal Rathore, Om Prakash Verma, Narendra Pratap Singh, Alok Das

published 24 Jun 2022

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Metabolic changes in vitamin D receptor knockout mice

Sue Lynn Lau, Rebecca A. Stokes, Beverly Ng, Kim Cheng, Roderick Clifton-Bligh, Jenny E. Gunton

published 17 Jun 2022

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Overexpression of VvASMT1 from grapevine enhanced salt and osmotic stress tolerance in Nicotiana benthamiana

Yanyan Yu, Yong Ni, Tian Qiao, Xiaomin Ji, Jinghao Xu, Bo Li, Qinghua Sun

published 16 Jun 2022

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Pattern of tamoxifen-induced Tie2 deletion in endothelial cells in mature blood vessels using endo SCL-Cre-ERT transgenic mice

Peter J. Zwiers, Rianne M. Jongman, Timara Kuiper, Jill Moser, Radu V. Stan, Joachim R. Göthert, Matijs van Meurs, Eliane R. Popa, Grietje Molema

published 08 Jun 2022

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Investigating CRISPR/Cas9 gene drive for production of disease-preventing prion gene alleles

Andrew R. Castle, Serene Wohlgemuth, Luis Arce, David Westaway

published 07 Jun 2022

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Impact of transgenic insect-resistant maize HGK60 with Cry1Ah gene on community components and biodiversity of arthropods in the fields

Yanjun Chen, Mengyun Ren, Libo Pan, Bo Liu, Xiao Guan, Jun Tao

published 03 Jun 2022

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Molecular characterization of a Novel NAD⁺-dependent farnesol dehydrogenase SoFLDH gene involved in sesquiterpenoid synthases from Salvia officinalis

Mohammed Ali, Elsayed Nishawy, Walaa A. Ramadan, Mohamed Ewas, Mokhtar Said Rizk, Ahmed G. M. Sief-Eldein, Mohamed Abd S. El-Zayat, Ahmed H. M. Hassan, Mingquan Guo, Guang-Wan Hu, Shengwei Wang, Fatma A. Ahmed, Mohamed Hamdy Amar, Qing-Feng Wang

published 03 Jun 2022

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Characterization of sucrose binding protein as a seed-specific promoter in transgenic tobacco Nicotiana tabacum L.

Nasibeh Chenarani, Abbasali Emamjomeh, Hassan Rahnama, Katayoun Zamani, Mahmoud Solouki

published 03 Jun 2022

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Resveratrol-nitric oxide donor hybrid effect on priapism in sickle cell and nitric oxide-deficient mouse

Andressa Kely Pinheiro, Dalila Andrade Pereira, Jean Leandro dos Santos, Fabiano Beraldi Calmasini, Eduardo Costa Alexandre, Leonardo Oliveira Reis, Arthur L. Burnett, Fernando Ferreira Costa, Fábio Henrique Silva

published 02 Jun 2022

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