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Genetic engineering

Inducible overexpression of a FAM3C/ILEI transgene has pleiotropic effects with shortened life span, liver fibrosis and anemia in mice

Ulrike Schmidt, Betül Uluca, Iva Vokic, Barizah Malik, Thomas Kolbe, Caroline Lassnig, Martin Holcmann, Veronica Moreno-Viedma, Bernhard Robl, Carina Mühlberger, Dagmar Gotthardt, Maria Sibilia, Thomas Rülicke, Mathias Müller, Agnes Csiszar

published 15 Sep 2023

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Transgenic expression of Arabidopsis ELONGATION FACTOR-TU RECEPTOR (AtEFR) gene in banana enhances resistance against Xanthomonas campestris pv. musacearum

Mark Adero, Jaindra Nath Tripathi, Richard Oduor, Cyril Zipfel, Leena Tripathi

published 01 Sep 2023

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Sertoli cell-enriched proteins in mouse and human testicular interstitial fluid

Liza O’Donnell, Laura F. Dagley, Michael Curley, Annalucia Darbey, Peter J. O’Shaughnessy, Thorsten Diemer, Adrian Pilatz, Daniela Fietz, Peter G. Stanton, Lee B. Smith, Diane Rebourcet

published 01 Sep 2023

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cis-Decalin-containing tetramic acids as inhibitors of insect steroidogenic glutathione S-transferase Noppera-bo

Naoki Kato, Kana Ebihara, Toshihiko Nogawa, Yushi Futamura, Kazue Inaba, Akiko Okano, Harumi Aono, Yuuta Fujikawa, Hideshi Inoue, Kazuhiko Matsuda, Hiroyuki Osada, Ryusuke Niwa, Shunji Takahashi

published 31 Aug 2023

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Elevated liver glycogenolysis mediates higher blood glucose during acute exercise in Barth syndrome

George G. Schweitzer, Grace L. Ditzenberger, Curtis C. Hughey, Brian N. Finck, Michael R. Martino, Christina A. Pacak, Barry J. Byrne, William Todd Cade

published 31 Aug 2023

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Helicase-like transcription factor (Hltf)-deletion activates Hmgb1-Rage axis and granzyme A-mediated killing of pancreatic β cells resulting in neonatal lethality

Gurvinder Kaur, Rebecca A. Helmer, Dalia Martinez-Marin, Souad R. Sennoune, Rachel L. Washburn, Raul Martinez-Zaguilan, Jannette M. Dufour, Beverly S. Chilton

published 25 Aug 2023

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Co-expression of nitrogenase proteins in cotton (Gossypium hirsutum L.)

Yimin Shang, Wenfang Guo, Xiaomeng Liu, Lei Ma, Dehu Liu, Sanfeng Chen

published 24 Aug 2023

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Social acceptance of genetic engineering technology

Katherine E. Koralesky, Lara V. Sirovica, Jillian Hendricks, Katelyn E. Mills, Marina A. G. von Keyserlingk, Daniel M. Weary

published 16 Aug 2023

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Reduced levels of A20 protein prompted RIPK1-dependent apoptosis and blood–brain barrier breakdown during cerebral ischemia reperfusion injury

Chaonan Yang, Yongjiao Wang, Xiaohui Wu, Min Gong, Ying Li

published 14 Aug 2023

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A sub-chronic feeding study of dual toxin insect-resistant transgenic maize (CEMB-413) on Wistar rats

Ayesha Liaqat, Ibrahim Bala Salisu, Allah Bakhsh, Qasim Ali, Ayesha Imran, Muhammad Azam Ali, Abdul Munim Farooq, Abdul Qayyum Rao, Ahmad Ali Shahid

published 09 Aug 2023

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N-dihydrogalactochitosan reduces mortality in a lethal mouse model of SARS-CoV-2

Christopher M. Weiss, Hongwei Liu, Erin E. Ball, Ashley R. Hoover, Talia S. Wong, Chun Fung Wong, Samuel Lam, Tomas Hode, M. Kevin Keel, Richard M. Levenson, Wei R. Chen, Lark L. Coffey

published 08 Aug 2023

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Oocyte-specific Wee1-like protein kinase 2 is dispensable for fertility in mice

Kaori Nozawa, Zian Liao, Yuhkoh Satouh, Ting Geng, Masahito Ikawa, Diana Monsivais, Martin M. Matzuk

published 01 Aug 2023

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Evaluation of an inducible knockout system in insect cells based on co-infection and CRISPR/Cas9

Christina Sophie Hausjell, Miriam Klausberger, Wolfgang Ernst, Reingard Grabherr

published 27 Jul 2023

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