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Genetic engineering

The PINK1/Parkin pathway of mitophagy exerts a protective effect during prion disease

Anne Ward, Forrest Jessop, Robert Faris, Jason Hollister, Daniel Shoup, Brent Race, Catharine M. Bosio, Suzette A. Priola

published 23 Feb 2024

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Successful expansion and cryopreservation of human natural killer cell line NK-92 for clinical manufacturing

Seul Lee, Yunjoo Joo, Eun Ji Lee, Youngseon Byeon, Jae-Hwan Kim, Kyoung-Ho Pyo, Young Seob Kim, Sun Min Lim, Peter Kilbride, Rohin K. Iyer, Mingming Li, Mandy C. French, Jung-Yub Lee, Jeeheon Kang, Hyesin Byun, Byoung Chul Cho

published 23 Feb 2024

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A comprehensive, improved protocol for generating common bean (Phaseolus vulgaris L.) transgenic hairy roots and their use in reverse-genetics studies

Ronal Pacheco, Georgina Estrada-Navarrete, Jorge Solis-Miranda, Noreide Nava, MA Juárez-Verdayes, Yolanda Ortega-Ortega, Carmen Quinto

published 21 Feb 2024

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Cloning of maize chitinase 1 gene and its expression in genetically transformed rice to confer resistance against rice blast caused by Pyricularia oryzae

Sadaf Anwaar, Nyla Jabeen, Khawaja Shafique Ahmad, Saima Shafique, Samra Irum, Hammad Ismail, Siffat Ullah Khan, Ateeq Tahir, Nasir Mehmood, Mark L. Gleason

published 16 Jan 2024

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High frequency of germline recombination in Nestin-Cre transgenic mice crossed with Glucagon-like peptide 1 receptor floxed mice

Yusuke Kajitani, Takashi Miyazawa, Tomoaki Inoue, Nao Kajitani, Masamichi Fujita, Yukina Takeichi, Yasutaka Miyachi, Ryuichi Sakamoto, Yoshihiro Ogawa

published 20 Dec 2023

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Hepatocellular Brg1 promotes CCl4-induced liver inflammation, ECM accumulation and fibrosis in mice

Baocai Wang, Benedikt Kaufmann, Carolin Mogler, Suyang Zhong, Yuhan Yin, Zhangjun Cheng, Roland M. Schmid, Helmut Friess, Norbert Hüser, Guido von Figura, Daniel Hartmann

published 30 Nov 2023

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Bacillus subtilis engineered for topical delivery of an antifungal agent

Veronica A. Montgomery, Ethan Cain, Mark P. Styczynski, Mark R. Prausnitz

published 30 Nov 2023

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Two mouse models of Alzheimer’s disease accumulate amyloid at different rates and have distinct Aβ oligomer profiles unaltered by ablation of cellular prion protein

Silvia A. Purro, Michael Farmer, Elizabeth Noble, Claire J. Sarell, Megan Powell, Daniel Yip, Lauren Giggins, Leila Zakka, David X. Thomas, Mark Farrow, Andrew J. Nicoll, Dominic Walsh, John Collinge

published 17 Nov 2023

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Female sex protects against renal edema, but not lung edema, in mice with partial deletion of the endothelial barrier regulator Tie2 compared to male sex

Anoek L. I. van Leeuwen, Elise Beijer, Roselique Ibelings, Nicole A. M. Dekker, Marjolein R. A. van der Steen, Joris J. T. H. Roelofs, Matijs van Meurs, Grietje Molema, Charissa E. van den Brom

published 16 Nov 2023

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Development of a sensitive real-time quaking-induced conversion (RT-QuIC) assay for application in prion-infected blood

Charlotte M. Thomas, M. Khalid F. Salamat, Christopher de Wolf, Sandra McCutcheon, A. Richard Alejo Blanco, Jean C. Manson, Nora Hunter, E. Fiona Houston

published 02 Nov 2023

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Exercise performance is not improved in mice with skeletal muscle deletion of natriuretic peptide clearance receptor

Brigitte Jia, Alexander Hasse, Fubiao Shi, Sheila Collins

published 02 Nov 2023

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A simple and efficient protocol for generating transgenic hairy roots using Agrobacterium rhizogenes

Shaun Ferguson, Nikolaj B. Abel, Dugald Reid, Lene H. Madsen, Thi-Bich Luu, Kasper R. Andersen, Jens Stougaard, Simona Radutoiu

published 01 Nov 2023

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U-Net based vessel segmentation for murine brains with small micro-magnetic resonance imaging reference datasets

Christoph Praschl, Lydia M. Zopf, Emma Kiemeyer, Ines Langthallner, Daniel Ritzberger, Adrian Slowak, Martin Weigl, Valentin Blüml, Nebojša Nešić, Miloš Stojmenović, Kathrin M. Kniewallner, Ludwig Aigner, Stephan Winkler, Andreas Walter

published 12 Oct 2023

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