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Gene silencing

Cleavage of MALAT1 RNA by 14-nt sgRNA-guided tRNase Z^L

Masayuki Takahashi, Masayuki Nashimoto

published 18 Sep 2025

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TGFBR1 gene silencing attenuates cardiomyopathy in the HFpEF mouse model

Xuanyang Shen, Weidong Li, Xiaolu Jiang, Hongfu Wen, Yuan Shen, Wen Zhang, Yongjian Peng, Guoping Kang

published 29 Aug 2025

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RNA-mediated gene silencing can reduce azole resistance, growth and pathogenicity in Pseudocercospora fijiensis

Flor Yuranny Canacuán Melo, Yohana Katerine Suárez Anaya, Vicente Emilio Rey Valenzuela, Juan Gonzalo Morales Osorio, Rafael Eduardo Arango Isaza

published 05 Jun 2025

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Gene silencing for invasive paper wasp management: Synthesized dsRNA can modify gene expression but did not affect mortality

Mariana Bulgarella, James W. Baty, Rose McGruddy, Philip J. Lester

published 03 Jan 2023

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Beyond identity: Understanding the contribution of the 5’ nucleotide of the antisense strand to RNAi activity

Peizhen Yang, Ericka Havecker, Matthew Bauer, Carl Diehl, Bill Hendrix, Paul Hoffer, Timothy Boyle, John Bradley, Amy Caruano-Yzermans, Jill Deikman

published 07 Sep 2021

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Systemic GFP silencing is associated with high transgene expression in Nicotiana benthamiana

Bill Hendrix, Paul Hoffer, Rick Sanders, Steve Schwartz, Wei Zheng, Brian Eads, Danielle Taylor, Jill Deikman

published 15 Mar 2021

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COPB2 gene silencing inhibits colorectal cancer cell proliferation and induces apoptosis via the JNK/c-Jun signaling pathway

Yan Wang, Guangmei Xie, Min Li, Juan Du, Min Wang

published 19 Nov 2020

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Hyaluronic acid/poly(ethylenimine) polyelectrolyte multilayer coatings for siRNA-mediated local gene silencing

Olivia Koenig, Bernd Neumann, Christian Schlensak, Hans Peter Wendel, Andrea Nolte

published 19 Mar 2019

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MicroRNA signature constituted of miR-30d, miR-93, and miR-181b is a promising prognostic marker in primary central nervous system lymphoma

Yasuo Takashima, Atsushi Kawaguchi, Yasuo Iwadate, Hiroaki Hondoh, Junya Fukai, Koji Kajiwara, Azusa Hayano, Ryuya Yamanaka

published 07 Jan 2019

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A wheat cytochrome P450 enhances both resistance to deoxynivalenol and grain yield

Lokanadha R. Gunupuru, Chanemougasoundharam Arunachalam, Keshav B. Malla, Amal Kahla, Alexandre Perochon, Jianguang Jia, Ganesh Thapa, Fiona M. Doohan

published 12 Oct 2018

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Protein kinase D3 modulates MMP1 and MMP13 expression in human chondrocytes

Jonathan Baker, Adrian M. D. Falconer, David J. Wilkinson, G. Nicholas Europe-Finner, Gary J. Litherland, Andrew D. Rowan

published 13 Apr 2018

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Dominance of P-glycoprotein 12 in phenotypic resistance conversion against ivermectin in Caenorhabditis elegans

Luiza Almeida Figueiredo, Thais Fuscaldi Rebouças, Sebastião Rodrigo Ferreira, Gabriela Flavia Rodrigues-Luiz, Rodrigo Cambraia Miranda, Ricardo Nascimento Araujo, Ricardo Toshio Fujiwara

published 23 Feb 2018

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A logic-based dynamic modeling approach to explicate the evolution of the central dogma of molecular biology

Mohieddin Jafari, Naser Ansari-Pour, Sadegh Azimzadeh, Mehdi Mirzaie

published 21 Dec 2017

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