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Gene expression and vector techniques

Advanced machine learning-guided optimization platform for high-yield soluble expression of Pseudomonas aeruginosa exotoxin A in engineered Escherichia coli strains

Shah Faisal Mohammad, Fawad Ali, Mamirkulova Shynara

published 10 Apr 2026

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hUMSCs-exo@Cyasterone protects the cell model of steroid-induced femur head necrosis by regulating N-glycosylation modification of CTSD-N258A

Youqiang Sun, Mengmeng Liang, Yuemeng Xing, Yifan Duan, Baogui Deng, Xiaobing Xiang

published 03 Apr 2026

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Salidroside protects against high-altitude hypoxia-induced kidney injury via regulation of renal dopamine D1-like receptors

Cheng Huan, Gan Zhilin, Xiao Dan, Wang Yue, Li Xianglian, Mo Liwen, Cheng Yue

published 31 Mar 2026

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Identification of BmSP25 gene in Bombyx mori with antiviral function against BmNPV

Yonghong Zhang, Yajin Li, Zhengqin Wang, Jiafu Luo, Lingli Li, Hongrui Zhang

published 27 Mar 2026

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Identification of autophagy-related key biomarkers in caerulein induced acute pancreatitis: In silico and in vivo study

Xinzhuang Shen, Jie Yao, Zongke Wang, Renhua Chen, Laian Li, Xiangjun Xu, Yongming Huang

published 27 Mar 2026

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Microalgal colony blot: A simple and rapid method for direct detection of recombinant protein production in microalgae colonies

Yasin Torres-Tiji, Francis J. Fields, Stephen P. Mayfield

published 25 Mar 2026

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Isolation methods influence the biological properties of Wharton’s Jelly-derived mesenchymal stem cells: A comparative study of yield, viability, proliferation, differentiation potential, and proteomic profiles

Jens Long Nguyen, Samih Mohamed-Ahmed, Ragda Saleem, Kamal Mustafa, Niyaz Al-Sharabi, Mariann Haavik Lysfjord Bentsen

published 20 Mar 2026

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Identification of novel plasma proteomic biomarkers of Dupuytren disease

Blake Hummer, Paola Sebastiani, Anastasia Leshchyk, Anastasia Gurinovich, Cecilie Bager, Morten Karsdal, Signe Nielsen, Charles Eaton

published 18 Mar 2026

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Functional effects of extracellular vesicles altered by a per- and polyfluoroalkyl substance mixture: In vitro liver cytotoxicity and proteomic expression alterations

Celeste K. Carberry, Angie L. Mordant, Christine A. Mills, Hadley Hartwell, Victoria F. Carberry, Lauren Simendinger, Elise Hickman, Laura E. Herring, Julia E. Rager

published 18 Mar 2026

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Comparison of neonatal systemic and intracerebroventricular AAV9 gene therapy delivery demonstrating improved behavioral and phenotypic outcomes in a mouse model of Niemann-Pick disease, type C1

Benjamin E. Epstein, Gabrielle M. Soden, Arturo A. Incao, Avani Mylvara, Jonathan Flynn, Fatih Ozsolak, William J. Pavan

published 11 Mar 2026

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Myc and Skp2 overexpression promotes p27 ubiquitination and degradation in Ewing Sarcoma

Yuta Kubota, Masanori Kawano, Ichiro Itonaga, Nobuhiro Kaku, Kazuhiro Tanaka

published 09 Mar 2026

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Serum proteomic characterization of stump-tailed macaques (Macaca arctoides) with neutralizing antibodies against Dengue virus in Thailand

Pakorn Ruengket, Sittiruk Roytrakul, Daraka Tongthainan, Kobporn Boonnak, Kanokwan Taruyanon, Bencharong Sangkharak, Wirasak Fungfuang

published 23 Feb 2026

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Analysis of EGFR signaling pathway; miRNAs and inflammatory biomarkers in a high-risk oral cancer population in Pakistan - An exploratory study

Namrah Anwar, Shahid Pervez, Tariq Moatter, Mitchell Stark, Qurratulain Chundriger, Tazeen Saeed Ali, Sohail Awan, Annika Antonsson

published 23 Feb 2026

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