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G protein coupled receptors

Computation suggests that the cell adhesion sub-proteome is enriched for sites of pH-dependence and charge burial

Shalaw Sallah, Jim Warwicker

Rapid purification of brain protein complexes containing active and inactive forms of the G protein Gα_o

Shubham Yadav, Satya Santoshi Veliventi, [ ... ], Santosh Kumar

Optimization of the prostaglandin F_2α receptor for structural biology

Marine Salze, Sébastien Chrétien, [ ... ], Martin Audet

Prediction of drug target interaction based on under sampling strategy and random forest algorithm

Feng Chen, Zhigang Zhao, [ ... ], Wenyan Wang

TAS2R5 screening reveals biased agonism that fails to evoke internalization and downregulation resulting in attenuated desensitization

Donghwa Kim, Hannah R. Strzelinski, Stephen B. Liggett

Complex regulation of Ca_v2.2 N-type Ca²⁺ channels by Ca²⁺ and G-proteins

Jessica R. Thomas, Jinglang Sun, Juan De la Rosa Vazquez, Amy Lee

Cross-species comparison of AlphaFold-derived G protein-coupled receptor structures reveals novel melatonin-related receptor in Neurospora crassa

Cathryn S. D. Maienza, Guillaume Lamoureux, Kwangwon Lee

Stimulation of insulin secretion induced by low 4-cresol dose involves the RPS6KA3 signalling pathway

François Brial, Géraldine Puel, [ ... ], Dominique Gauguier

Single-cell transcriptomic atlas of enteroendocrine cells along the murine gastrointestinal tract

Christopher A. Smith, Elisabeth A. A. O’Flaherty, [ ... ], Fiona M. Gribble

Role of canonical and non-canonical cAMP sources in CRHR2α-dependent signaling

Natalia G. Armando, Paula A. dos Santos Claro, [ ... ], Susana Silberstein

Descriptive molecular pharmacology of the δ opioid receptor (DOR): A computational study with structural approach

Guillermo Goode-Romero, Laura Dominguez

Differential activation of rhodopsin triggers distinct endocytic trafficking and recycling in vivo via differential phosphorylation

Darwin Ferng, Wesley Sun, Bih-Hwa Shieh

Chemical range recognized by the ligand-binding domain in a representative amino acid-sensing taste receptor, T1r2a/T1r3, from medaka fish

Hikaru Ishida, Norihisa Yasui, Atsuko Yamashita

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