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Fluorimetry

Grifolin, neogrifolin and confluentin from the terricolous polypore Albatrellus flettii suppress KRAS expression in human colon cancer cells

Almas Yaqoob, Wai Ming Li, Victor Liu, Chuyi Wang, Sebastian Mackedenski, Linda E. Tackaberry, Hugues B. Massicotte, Keith N. Egger, Kerry Reimer, Chow H. Lee

published 05 May 2020

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m⁶A minimally impacts the structure, dynamics, and Rev ARM binding properties of HIV-1 RRE stem IIB

Chia-Chieh Chu, Bei Liu, Raphael Plangger, Christoph Kreutz, Hashim M. Al-Hashimi

published 11 Dec 2019

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Highly sensitive biomolecular interaction detection method using optical bound/free separation with grating-coupled surface plasmon field-enhanced fluorescence spectroscopy (GC-SPFS)

Takatoshi Kaya, Satoru Nagatoishi, Kosuke Nagae, Yukito Nakamura, Kohei Tsumoto

published 01 Aug 2019

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Substituted anthraquinones represent a potential scaffold for DNA methyltransferase 1-specific inhibitors

Rebecca L. Switzer, Jessica Medrano, David A. Reedel, Jill Weiss

published 15 Jul 2019

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The N-terminal region of photocleavable peptides that bind HLA-DR1 determines the kinetics of fragment release

Maria Pia Negroni, Lawrence J. Stern

published 02 Jul 2018

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Investigation of FoxO3 dynamics during erythroblast development in β-thalassemia major

Naruchit Thanuthanakhun, Lalana Nuntakarn, Somponnat Sampattavanich, Usanarat Anurathapan, Suphanun Phuphanitcharoenkun, Savichaya Pornpaiboonstid, Suparerk Borwornpinyo, Suradej Hongeng

published 03 Nov 2017

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A highly-sensitive high throughput assay for dynamin's basal GTPase activity

Aparna Mohanakrishnan, Triet Vincent M. Tran, Meera Kumar, Hong Chen, Bruce A. Posner, Sandra L. Schmid

published 28 Sep 2017

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Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay

Justin Hall, Amy Brault, Fabien Vincent, Shawn Weng, Hong Wang, Darren Dumlao, Ann Aulabaugh, Dikran Aivazian, Dana Castro, Ming Chen, Jeffrey Culp, Ken Dower, Joseph Gardner, Steven Hawrylik, Douglas Golenbock, David Hepworth, Mark Horn, Lyn Jones, Peter Jones, Eicke Latz, Jing Li, Lih-Ling Lin, Wen Lin, David Lin, Frank Lovering, Nootaree Niljanskul, Ryan Nistler, Betsy Pierce, Olga Plotnikova, Daniel Schmitt, Suman Shanker, James Smith, William Snyder, Timothy Subashi, John Trujillo, Edyta Tyminski, Guoxing Wang, Jimson Wong, Bruce Lefker, Leslie Dakin, Karen Leach

published 21 Sep 2017

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Directed evolution provides insight into conformational substrate sampling by SrtA

Muna Suliman, Vishaka Santosh, Tom C. M. Seegar, Annamarie C. Dalton, Kathryn M. Schultz, Candice S. Klug, William A. Barton

published 31 Aug 2017

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Evidence for pleural epithelial-mesenchymal transition in murine compensatory lung growth

Alexandra B. Ysasi, Willi L. Wagner, Cristian D. Valenzuela, Arne Kienzle, Andrew B. Servais, Robert D. Bennett, Akira Tsuda, Maximilian Ackermann, Steven J. Mentzer

published 19 May 2017

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Cell cycle profiling by image and flow cytometry: The optimised protocol for the detection of replicational activity using 5-Bromo-2′-deoxyuridine, low concentration of hydrochloric acid and exonuclease III

Anna Ligasová, Petr Konečný, Ivo Frydrych, Karel Koberna

published 20 Apr 2017

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Looking for ugly ducklings: The role of the stability of BrdU-antibody complex and the improved method of the detection of DNA replication

Anna Ligasová, Petr Konečný, Ivo Frydrych, Karel Koberna

published 30 Mar 2017

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Applying a high-throughput fluorescence polarization assay for the discovery of chemical probes blocking La:RNA interactions in vitro and in cells

Gunhild Sommer, Alena Fedarovich, Venkatesh Kota, Reycel Rodriguez, Charles D. Smith, Tilman Heise

published 14 Mar 2017

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