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Fc receptors

Blockade of mTOR ameliorates IgA nephropathy by correcting CD89 and CD71 dysfunctions in humanized mice

Alexandra Cambier, Jennifer Da Silva, Julie Bex, Fanny Canesi, Lison Lachize Neanne, Aurélie Sannier, Hélène Mathieu, Erwan Boedec, Amandine Badie, Renato C. Monteiro

published 07 Oct 2025

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Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM

Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, the Emory-Sage-SGC TREAT-AD Center , Alison D. Axtman

published 15 Feb 2024

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Analytical comparability to evaluate impact of manufacturing changes of ARX788, an Anti-HER2 ADC in late-stage clinical development

Wayne Yu, Mysore P. Ramprasad, Manoj Pal, Chris Chen, Shashi Paruchuri, Lillian Skidmore, Nick Knudsen, Molly Allen, Ying Buechler

published 10 Jul 2023

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Evaluation of strategies to modify Anti-SARS-CoV-2 monoclonal antibodies for optimal functionality as therapeutics

Robert V. House, Thomas A. Broge, Todd J. Suscovich, Doris M. Snow, Milan T. Tomic, Genevieve Nonet, Kamaljit Bajwa, Guangyu Zhu, Zachary Martinez, Kyal Hackett, Christopher G. Earnhart, Nicole M. Dorsey, Svetlana A. Hopkins, Dalia S. Natour, Heather D. Davis, Michael S. Anderson, Melicia R. Gainey, Ronald R. Cobb

published 03 Jun 2022

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Anti-SARS-CoV-2 IgG and IgA antibodies in COVID-19 convalescent plasma do not enhance viral infection

Natasha M. Clark, Sanath Kumar Janaka, William Hartman, Susan Stramer, Erin Goodhue, John Weiss, David T. Evans, Joseph P. Connor

published 08 Mar 2022

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Fc-engineered antibodies with immune effector functions completely abolished

Ian Wilkinson, Stephen Anderson, Jeremy Fry, Louis Alex Julien, David Neville, Omar Qureshi, Gary Watts, Geoff Hale

published 21 Dec 2021

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Functional in vitro assessment of modified antibodies: Impact of label on protein properties

Martin R. Edelmann, Simon Hauri

published 16 Sep 2021

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No evidence for hypogammaglobulinemia in patients with paroxysmal nocturnal hemoglobinuria (PNH) chronically treated with ravulizumab

Ferras Alashkar, Scott Rottinghaus, Colin Vance, Dörte Herich-Terhürne, Ulrich Dührsen, Roland Assert, Alexander Röth

published 27 Mar 2020

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Characterization of NF-κB Reporter U937 Cells and Their Application for the Detection of Inflammatory Immune-Complexes

Csilla Kecse-Nagy, Zoltán Szittner, Krisztián Papp, Zoltán Hegyi, Paolo Rovero, Paola Migliorini, Veronika Lóránd, László Homolya, József Prechl

published 27 May 2016

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Expression Profile of Human Fc Receptors in Mucosal Tissue: Implications for Antibody-Dependent Cellular Effector Functions Targeting HIV-1 Transmission

Hannah M. Cheeseman, Ann M. Carias, Abbey B. Evans, Natalia J. Olejniczak, Paul Ziprin, Deborah F. L. King, Thomas J. Hope, Robin J. Shattock

published 10 May 2016

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Variation at FCGR2A and Functionally Related Genes Is Associated with the Response to Anti-TNF Therapy in Rheumatoid Arthritis

Gabriela Avila-Pedretti, Jesús Tornero, Antonio Fernández-Nebro, Francisco Blanco, Isidoro González-Alvaro, Juan D. Cañete, Joan Maymó, Mercedes Alperiz, Benjamín Fernández-Gutiérrez, Alex Olivé, Héctor Corominas, Alba Erra, Adrià Aterido, María López Lasanta, Raül Tortosa, Antonio Julià, Sara Marsal

published 07 Apr 2015

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Fc Receptors for Immunoglobulins and Their Appearance during Vertebrate Evolution

Srinivas Akula, Sayran Mohammadamin, Lars Hellman

published 09 May 2014

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Functional Fcgamma Receptor Polymorphisms Are Associated with Human Allergy

Jianming Wu, Rui Lin, Jinhai Huang, Weihua Guan, William S. Oetting, P. Sriramarao, Malcolm N. Blumenthal

published 21 Feb 2014

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