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Fc receptors

Blockade of mTOR ameliorates IgA nephropathy by correcting CD89 and CD71 dysfunctions in humanized mice

Alexandra Cambier, Jennifer Da Silva, [ ... ], Renato C. Monteiro

Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM

Frances M. Bashore, Vittorio L. Katis, [ ... ], Alison D. Axtman

Analytical comparability to evaluate impact of manufacturing changes of ARX788, an Anti-HER2 ADC in late-stage clinical development

Wayne Yu, Mysore P. Ramprasad, [ ... ], Ying Buechler

Evaluation of strategies to modify Anti-SARS-CoV-2 monoclonal antibodies for optimal functionality as therapeutics

Robert V. House, Thomas A. Broge, [ ... ], Ronald R. Cobb

Anti-SARS-CoV-2 IgG and IgA antibodies in COVID-19 convalescent plasma do not enhance viral infection

Natasha M. Clark, Sanath Kumar Janaka, [ ... ], Joseph P. Connor

Fc-engineered antibodies with immune effector functions completely abolished

Ian Wilkinson, Stephen Anderson, [ ... ], Geoff Hale

Functional in vitro assessment of modified antibodies: Impact of label on protein properties

Martin R. Edelmann, Simon Hauri

No evidence for hypogammaglobulinemia in patients with paroxysmal nocturnal hemoglobinuria (PNH) chronically treated with ravulizumab

Ferras Alashkar, Scott Rottinghaus, [ ... ], Alexander Röth

Characterization of NF-κB Reporter U937 Cells and Their Application for the Detection of Inflammatory Immune-Complexes

Csilla Kecse-Nagy, Zoltán Szittner, [ ... ], József Prechl

Expression Profile of Human Fc Receptors in Mucosal Tissue: Implications for Antibody-Dependent Cellular Effector Functions Targeting HIV-1 Transmission

Hannah M. Cheeseman, Ann M. Carias, [ ... ], Robin J. Shattock

Variation at FCGR2A and Functionally Related Genes Is Associated with the Response to Anti-TNF Therapy in Rheumatoid Arthritis

Gabriela Avila-Pedretti, Jesús Tornero, [ ... ], Sara Marsal

Fc Receptors for Immunoglobulins and Their Appearance during Vertebrate Evolution

Srinivas Akula, Sayran Mohammadamin, Lars Hellman

Functional Fcgamma Receptor Polymorphisms Are Associated with Human Allergy

Jianming Wu, Rui Lin, [ ... ], Malcolm N. Blumenthal

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