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Epimastigotes

Validation of Trypanosoma cruzi inactivation techniques for laboratory use

Lorna M. MacLean, Mark Ariyanayagam, Lalitha Sastry, Christy Paterson, Manu De Rycker, Alan H. Fairlamb

published 18 Apr 2024

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Extensible membrane nanotubules mediate attachment of Trypanosoma cruzi epimastigotes under flow

Cristhian David Perdomo-Gómez, Nancy E. Ruiz-Uribe, John Mario González, Manu Forero-Shelton

published 22 Mar 2023

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Trypanosoma cruzi PARP is enriched in the nucleolus and is present in a thread connecting nuclei during mitosis

María Laura Kevorkian, Salomé C. Vilchez Larrea, Silvia H. Fernández Villamil

published 30 Dec 2022

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Drug repurposing for Chagas disease: In vitro assessment of nimesulide against Trypanosoma cruzi and insights on its mechanisms of action

Joana D’Arc S. Trindade, Célio Geraldo Freire-de-Lima, Suzana Côrte-Real, Debora Decote-Ricardo, Marco Edilson Freire de Lima

published 22 Oct 2021

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Characterization and trypanocidal activity of a β-lapachone-containing drug carrier

Juliana M. C. Barbosa, Caroline D. Nicoletti, Patrícia B. da Silva, Tatiana G. Melo, Débora O. Futuro, Vitor F. Ferreira, Kelly Salomão

published 04 Mar 2021

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The ubiquinone synthesis pathway is a promising drug target for Chagas disease

Takeshi Nara, Yukari Nakagawa, Keiko Tsuganezawa, Hitomi Yuki, Katsuhiko Sekimata, Hiroo Koyama, Naoko Ogawa, Teruki Honma, Mikako Shirouzu, Takehiro Fukami, Yuichi Matsuo, Daniel Ken Inaoka, Kiyoshi Kita, Akiko Tanaka

published 04 Feb 2021

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Synergistic effect and ultrastructural changes in Trypanosoma cruzi caused by isoobtusilactone A in short exposure of time

Júlio Menta de Almeida, Felipe Oliveira Nunes, Lígia Fernanda Ceole, Tabata D’Maiella Freitas Klimeck, Letícia Alves da Cruz, Danilo Tófoli, Beatriz Santana Borges, Walmir Silva Garcez, Inês Aparecida Tozetti, Lia Carolina Soares Medeiros, Fernanda Rodrigues Garcez, Alda Maria Teixeira Ferreira

published 28 Jan 2021

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If host is refractory, insistent parasite goes berserk: Trypanosomatid Blastocrithidia raabei in the dock bug Coreus marginatus

Alexander O. Frolov, Marina N. Malysheva, Anna I. Ganyukova, Viktoria V. Spodareva, Jana Králová, Vyacheslav Yurchenko, Alexei Y. Kostygov

published 16 Jan 2020

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Obligate development of Blastocrithidia papi (Trypanosomatidae) in the Malpighian tubules of Pyrrhocoris apterus (Hemiptera) and coordination of host-parasite life cycles

Alexander O. Frolov, Marina N. Malysheva, Anna I. Ganyukova, Vyacheslav Yurchenko, Alexei Y. Kostygov

published 27 Sep 2018

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Phenotypic diversity and drug susceptibility of Trypanosoma cruzi TcV clinical isolates

Luz P. Quebrada Palacio, Mariela N. González, Yolanda Hernandez-Vasquez, Alina E. Perrone, Adriana Parodi-Talice, Jacqueline Bua, Miriam Postan

published 05 Sep 2018

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Transcriptome-wide analysis of the Trypanosoma cruzi proliferative cycle identifies the periodically expressed mRNAs and their multiple levels of control

Santiago Chávez, Guillermo Eastman, Pablo Smircich, Lorena Lourdes Becco, Carolina Oliveira-Rizzo, Rafael Fort, Mariana Potenza, Beatriz Garat, José Roberto Sotelo-Silveira, María Ana Duhagon

published 28 Nov 2017

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Knockout of the gamma subunit of the AP-1 adaptor complex in the human parasite Trypanosoma cruzi impairs infectivity and differentiation and prevents the maturation and targeting of the major protease cruzipain

Claudia Maria do Nascimento Moreira, Cassiano Martin Batista, Jessica Chimenes Fernandes, Rafael Luis Kessler, Maurilio José Soares, Stenio Perdigão Fragoso

published 31 Jul 2017

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Antioxidant, antimicrobial, antiparasitic, and cytotoxic properties of various Brazilian propolis extracts

Rejane Pina Dantas Silva, Bruna Aparecida Souza Machado, Gabriele de Abreu Barreto, Samantha Serra Costa, Luciana Nalone Andrade, Ricardo Guimarães Amaral, Adriana Andrade Carvalho, Francine Ferreira Padilha, Josiane Dantas Viana Barbosa, Marcelo Andres Umsza-Guez

published 30 Mar 2017

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