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Epigenetic therapy

Contrasting effects of DNA demethylation on cancer-germline gene expression in breast cancer and leukemia cells

Mikhlid H. Almutairi, Turki M. Alrubie

Integrative analysis of epigenetic subtypes in acute myeloid Leukemia: A multi-center study combining machine learning for prognostic and therapeutic insights

Jincan Li, Shengyue Wang

Epigenome-wide methylation analysis shows phosphonoethylamine alleviates aberrant DNA methylation in NASH caused by Pcyt2 deficiency

Sophie Grapentine, Prasoon Agarwal, Vernon W. Dolinsky, Marica Bakovic

Increased scalability and sequencing quality of an epigenetic age prediction assay

Benjamin Mayne, David Chandler, [ ... ], Oliver Berry

Epigenetic regulation in colorectal cancer: The susceptibility of microRNAs 145, 143 and 133b to DNA demethylation and histone deacetylase inhibitors

Aadilah Omar, Drishna Govan, Clement Penny

Effects of TSA, NaB, Aza in Lactuca sativa L. protoplasts and effect of TSA in Nicotiana benthamiana protoplasts on cell division and callus formation

Seung Hee Choi, Woo Seok Ahn, [ ... ], Suk Weon Kim

Single-cell analysis of a high-grade serous ovarian cancer cell line reveals transcriptomic changes and cell subpopulations sensitive to epigenetic combination treatment

Shruthi Sriramkumar, Tara X. Metcalfe, [ ... ], Kenneth P. Nephew

Epigenetic and transcriptome responsiveness to ER modulation by tissue selective estrogen complexes in breast epithelial and breast cancer cells

Terri L. Messier, Joseph R. Boyd, [ ... ], Gary S. Stein

Xeno- and transgene-free reprogramming of mesenchymal stem cells toward the cells expressing neural markers using exosome treatments

Luis Sebástian Alexis Valerio, Kiminobu Sugaya

Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer

Ping-Ching Hsu, Susan A. Kadlubar, [ ... ], Issam Makhoul

Revealing the epigenetic effect of temozolomide on glioblastoma cell lines in therapeutic conditions

Agnieszka Belter, Jakub Barciszewski, Anna-Maria Barciszewska

Small molecule inhibition of lysine-specific demethylase 1 (LSD1) and histone deacetylase (HDAC) alone and in combination in Ewing sarcoma cell lines

Darcy Welch, Elliot Kahen, [ ... ], Damon R. Reed

RG108 increases NANOG and OCT4 in bone marrow-derived mesenchymal cells through global changes in DNA modifications and epigenetic activation

Rahyza I. F. Assis, Malgorzata Wiench, [ ... ], Denise C. Andia

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