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Enzymology

High Cooperativity of the SV40 Major Capsid Protein VP1 in Virus Assembly

Santanu Mukherjee, Mahmoud Abd-El-Latif, [ ... ], Ariella Oppenheim

Computer-Aided Lead Optimization: Improved Small-Molecule Inhibitor of the Zinc Endopeptidase of Botulinum Neurotoxin Serotype A

Jing Tang, Jewn Giew Park, [ ... ], Yuan-Ping Pang

Systems Analysis of N-Glycan Processing in Mammalian Cells

Patrick Hossler, Bhanu Chandra Mulukutla, Wei-Shou Hu

The Tricarboxylic Acid Cycle, an Ancient Metabolic Network with a Novel Twist

Ryan J. Mailloux, Robin Bériault, [ ... ], Vasu D. Appanna

Screen for ISG15-crossreactive Deubiquitinases

André Catic, Edda Fiebiger, [ ... ], Hidde L. Ploegh

A Modern Mode of Activation for Nucleic Acid Enzymes

Dominique Lévesque, Francis P. Brière, Jean-Pierre Perreault

Formaldehyde at Low Concentration Induces Protein Tau into Globular Amyloid-Like Aggregates In Vitro and In Vivo

Chun Lai Nie, Yan Wei, [ ... ], Rong Giao He

Simultaneous Activation of Complement and Coagulation by MBL-Associated Serine Protease 2

Anders Krarup, Russell Wallis, [ ... ], Robert B. Sim

X-ray Structures of the Signal Recognition Particle Receptor Reveal Targeting Cycle Intermediates

Christopher L. Reyes, Earl Rutenber, Peter Walter, Robert M. Stroud

Treatment of Fabry Disease: Outcome of a Comparative Trial with Agalsidase Alfa or Beta at a Dose of 0.2 mg/kg

Anouk C. Vedder, Gabor E. Linthorst, [ ... ], Carla E.M. Hollak

Protein-Tyrosine Kinase Activity Profiling in Knock Down Zebrafish Embryos

Simone Lemeer, Chris Jopling, [ ... ], Jeroen den Hertog

Hexose-6-phosphate Dehydrogenase Modulates 11β-Hydroxysteroid Dehydrogenase Type 1-Dependent Metabolism of 7-keto- and 7β-hydroxy-neurosteroids

Lyubomir G. Nashev, Charlie Chandsawangbhuwana, [ ... ], Alex Odermatt

Silencing and Un-silencing of Tetracycline-Controlled Genes in Neurons

Peixin Zhu, M. Isabel Aller, [ ... ], Mazahir T. Hasan

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