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Enzymology

Lactate dehydrogenase is an indicator for outcomes of short-term and long-term in septic patients

Zhao Zeng, Cuirong Guo, Fengning Tang, Ning Ding

published 08 Dec 2025

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Inflammatory cytokines promote interferon regulatory factor (IRF) transcriptional activity in human pulmonary epithelial cells through the induction of IRF1 by nuclear factor-κB

Amandah Necker-Brown, Mahmoud M. Mostafa, Andrei Georgescu, Andrew J. Thorne, Priyanka Chandramohan, Cora Kooi, Keerthana Kalyanaraman, Alex Gao, Akanksha Bansal, Sarah K. Sasse, Anthony N. Gerber, Richard Leigh, Robert Newton

published 08 Dec 2025

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Circular RNA FTO functions as a hsa-miR-141-3p sponge to regulate the growth and migration abilities of human retinal endothelial cells via up-regulating ZEB1

Yaoyao Chen, Renjian Hu, Enhui Li, Gaochun Li, Bing Xia, Jie Zhou

published 05 Dec 2025

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Stochastic model highlights the impact of crystallinity on saccharification dynamics depending on plant chemotype and pre-treatment

Partho Sakha De, Philipp M Grande, Henrike Heise, Holger Klose, Adélaïde Raguin

published 05 Dec 2025

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Lysine p-nitroanilide impairs cellular energetics and potentiates statin-induced cytotoxicity in RD rhabdomyosarcoma cells

Johan Alvarado-Calderón, Guillermo Juárez-Vega, Jesús Rosendo Martínez-Arellano, Hilda Sánchez-Vidal, Imelda Cecilia Zarzoza-Mendoza, David Morales-Morales, Juan Manuel Germán-Acacio, Rogelio Rodríguez-Sotres, Lilia G. Noriega, José Carlos Páez-Franco

published 04 Dec 2025

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Effects of cotton straw biochar on methane emissions using rumen simulations

Shiqi Zhang, Yaqian Zhang, Yankun Zhao, Nan Zheng, He Chen

published 04 Dec 2025

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Low level of plasma DNase is associated with worse clinical outcome in testicular germ cell tumor patients and exogeneous DNase I improves (Leverages) cisplatin treatment efficacy

Mego Michal, Vlkova Barbora, Kalavska Katarina, Pastorek Michal, Cierna Zuzana, Sestakova Zuzana, Chovanec Miroslav, Udvorkova Natalia, Kucerova Lucia, Celec Peter

published 04 Dec 2025

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Renal and hepatic function is preserved following inducible knockout of kynurenine pathway enzymes KMO or QPRT in adult mice

Benjamin S. Summers, Luke Milham, Sonia Bustamante, Krishan Gondal, Peggy Rentsch, Gayathri Sundaram, Michael D. Lovelace, Bryce Vissel, Bruce J. Brew

published 04 Dec 2025

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Comparative effectiveness of adjuvant treatment for hepatocellular carcinoma with high risk of recurrence: A systematic review and network meta-analysis

Zha Peng, Leigu Shen, Yaqiong Wang, Boyu Chen, Zhuangrong Zhu, Chengyi He, Hai Huang

published 04 Dec 2025

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Rational design of novel Plasmodium falciparum glutamyl-tRNA synthetase inhibitors for the development of next-generation antimalarial drugs

Wesam Nofal

published 04 Dec 2025

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Moringa oleifera potential for the treatment and prevention of COVID-19 involving molecular interaction, antioxidant properties and kinetic mechanism

Mamoudou Hamadou, Christian Bernard Bakwo Bassogog, Fookalbo Vagai Obadias, Abras Djaffi Assaly, Martin Alain Mune Mune

published 03 Dec 2025

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Comparison of Atezolizumab plus Aevacizumab and Atezolizumab plus Aabozantinib for advanced hepatocellular carcinoma: A cost-effectiveness analysis

Heng Xiang, Zhihua She, Liting Wang, Ye Peng, Lei Zhang, Chongqing Tan

published 03 Dec 2025

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Translocation of benzo(a)pyrene reactive metabolites across human mammary epithelial cell membranes

B. Alex Merrick, Ashley M. Brooks, Julie F. Foley, Betty K. Mansfield, James K. Selkirk

published 03 Dec 2025

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