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Enzyme structure

Crystal Structure of the Pyrazinamidase of Mycobacterium tuberculosis: Insights into Natural and Acquired Resistance to Pyrazinamide

Stéphanie Petrella, Nathalie Gelus-Ziental, Arnaud Maudry, Caroline Laurans, Rachid Boudjelloul, Wladimir Sougakoff

published 24 Jan 2011

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Structural Basis of Enzymatic Activity for the Ferulic Acid Decarboxylase (FADase) from Enterobacter sp. Px6-4

Wen Gu, Jinkui Yang, Zhiyong Lou, Lianming Liang, Yuna Sun, Jingwen Huang, Xuemei Li, Yi Cao, Zhaohui Meng, Ke-Qin Zhang

published 21 Jan 2011

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Identification of Critical Residues of the Mycobacterial Dephosphocoenzyme A Kinase by Site-Directed Mutagenesis

Guneet Walia, Komatireddy Gajendar, Avadhesha Surolia

published 11 Jan 2011

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Nuclear Shield: A Multi-Enzyme Task-Force for Nucleus Protection

Raffaele Fabrini, Alessio Bocedi, Valentina Pallottini, Lorena Canuti, Michele De Canio, Andrea Urbani, Valeria Marzano, Tommaso Cornetta, Pasquale Stano, Anna Giovanetti, Lorenzo Stella, Antonella Canini, Giorgio Federici, Giorgio Ricci

published 10 Dec 2010

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Evolutionary Innovations and the Organization of Protein Functions in Genotype Space

Evandro Ferrada, Andreas Wagner

published 30 Nov 2010

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Crystal Structure of the 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase•Dihydropteroate Synthase Bifunctional Enzyme from Francisella tularensis

Charles W. Pemble IV, Perdeep K. Mehta, Smriti Mehra, Zhenmei Li, Amanda Nourse, Richard E. Lee, Stephen W. White

published 30 Nov 2010

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Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase: Biochemical Features of a Crucial Enzyme for Mycobacterial Cell Wall Biosynthesis

Anna P. Lucarelli, Silvia Buroni, Maria R. Pasca, Menico Rizzi, Andrea Cavagnino, Giovanna Valentini, Giovanna Riccardi, Laurent R. Chiarelli

published 15 Nov 2010

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Structural Relationships in the Lysozyme Superfamily: Significant Evidence for Glycoside Hydrolase Signature Motifs

Alexandre Wohlkönig, Joëlle Huet, Yvan Looze, René Wintjens

published 09 Nov 2010

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AAV-Mediated Gene Delivery in Adult GM1-Gangliosidosis Mice Corrects Lysosomal Storage in CNS and Improves Survival

Rena C. Baek, Marike L. D. Broekman, Stanley G. Leroy, Laryssa A. Tierney, Michael A. Sandberg, Alessandra d'Azzo, Thomas N. Seyfried, Miguel Sena-Esteves

published 18 Oct 2010

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Catalytic Mechanism of Cellulose Degradation by a Cellobiohydrolase, CelS

Moumita Saharay, Hong Guo, Jeremy C. Smith

published 12 Oct 2010

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Characterization of a Novel Esterase Rv0045c from Mycobacterium tuberculosis

Jiubiao Guo, Xiangdong Zheng, Lipeng Xu, Zhongyuan Liu, Kehui Xu, Shentao Li, Tingyi Wen, Siguo Liu, Hai Pang

published 01 Oct 2010

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Crystal Structure of Human AKT1 with an Allosteric Inhibitor Reveals a New Mode of Kinase Inhibition

Wen-I Wu, Walter C. Voegtli, Hillary L. Sturgis, Faith P. Dizon, Guy P. A. Vigers, Barbara J. Brandhuber

published 23 Sep 2010

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Active Site Conformational Dynamics in Human Uridine Phosphorylase 1

Tarmo P. Roosild, Samantha Castronovo

published 14 Sep 2010

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