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Enzyme structure

Insights into the Mechanism of Bovine CD38/NAD+Glycohydrolase from the X-Ray Structures of Its Michaelis Complex and Covalently-Trapped Intermediates

Pascal F. Egea, Hélène Muller-Steffner, Isabelle Kuhn, Céline Cakir-Kiefer, Norman J. Oppenheimer, Robert M. Stroud, Esther Kellenberger, Francis Schuber

published 18 Apr 2012

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Insight on an Arginine Synthesis Metabolon from the Tetrameric Structure of Yeast Acetylglutamate Kinase

Sergio de Cima, Fernando Gil-Ortiz, Marjolaine Crabeel, Ignacio Fita, Vicente Rubio

published 18 Apr 2012

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Analyses of the Large Subunit Histidine-Rich Motif Expose an Alternative Proton Transfer Pathway in [NiFe] Hydrogenases

Emma Szőri-Dorogházi, Gergely Maróti, Milán Szőri, Andrea Nyilasi, Gábor Rákhely, Kornél L. Kovács

published 12 Apr 2012

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Modulation of γ-Secretase Activity by Multiple Enzyme-Substrate Interactions: Implications in Pathogenesis of Alzheimer's Disease

Željko M. Svedružić, Katarina Popović, Ivana Smoljan, Vesna Šendula-Jengić

published 30 Mar 2012

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Structures of Helicobacter pylori Shikimate Kinase Reveal a Selective Inhibitor-Induced-Fit Mechanism

Wen-Chi Cheng, Yen-Fu Chen, Hung-Jung Wang, Kai-Cheng Hsu, Shuang-Chih Lin, Tzu-Jung Chen, Jinn-Moon Yang, Wen-Ching Wang

published 16 Mar 2012

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The 3′-Terminal Hexamer Sequence of Classical swine fever virus RNA Plays a Role in Negatively Regulating the IRES-Mediated Translation

Shih-Wei Huang, Meng-Yu Chan, Wei-Li Hsu, Chin-Cheng Huang, Ching-Hsiu Tsai

published 14 Mar 2012

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Loss and Recovery of Mgat3 and GnT-III Mediated E-cadherin N-glycosylation Is a Mechanism Involved in Epithelial-Mesenchymal-Epithelial Transitions

Salomé S. Pinho, Patrícia Oliveira, Joana Cabral, Sandra Carvalho, David Huntsman, Fátima Gärtner, Raquel Seruca, Celso A. Reis, Carla Oliveira

published 13 Mar 2012

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Perineuronal Nets Play a Role in Regulating Striatal Function in the Mouse

Hyunchul Lee, Catherine A. Leamey, Atomu Sawatari

published 12 Mar 2012

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Quantitative Analysis of the Effective Functional Structure in Yeast Glycolysis

Ildefonso M. De la Fuente, Jesus M. Cortes

published 29 Feb 2012

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A Catalytic Mechanism for Cysteine N-Terminal Nucleophile Hydrolases, as Revealed by Free Energy Simulations

Alessio Lodola, Davide Branduardi, Marco De Vivo, Luigi Capoferri, Marco Mor, Daniele Piomelli, Andrea Cavalli

published 28 Feb 2012

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Structural and Functional Analysis of Validoxylamine A 7′-phosphate Synthase ValL Involved in Validamycin A Biosynthesis

Lina Zheng, Xiang Zhou, Huaidong Zhang, Xiaofeng Ji, Lei Li, Lin Huang, Linquan Bai, Houjin Zhang

published 27 Feb 2012

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Carbinolamine Formation and Dehydration in a DNA Repair Enzyme Active Site

M. L. Dodson, Ross C. Walker, R. Stephen Lloyd

published 22 Feb 2012

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New Insight into the Transcarbamylase Family: The Structure of Putrescine Transcarbamylase, a Key Catalyst for Fermentative Utilization of Agmatine

Luis Mariano Polo, Fernando Gil-Ortiz, Angel Cantín, Vicente Rubio

published 20 Feb 2012

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