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Enzyme structure

Sphingomyelinase D Activity in Model Membranes: Structural Effects of in situ Generation of Ceramide-1-Phosphate

Roberto P. Stock, Jonathan Brewer, [ ... ], Luis A. Bagatolli

Assessment of Pseudomonas aeruginosa N⁵,N¹⁰-Methylenetetrahydrofolate Dehydrogenase - Cyclohydrolase as a Potential Antibacterial Drug Target

Thomas C. Eadsforth, Mary Gardiner, [ ... ], William N. Hunter

Structure of an Enzyme-Derived Phosphoprotein Recognition Domain

Christopher A. Johnston, Chris Q. Doe, Kenneth E. Prehoda

Insights into the Mechanism of Bovine CD38/NAD+Glycohydrolase from the X-Ray Structures of Its Michaelis Complex and Covalently-Trapped Intermediates

Pascal F. Egea, Hélène Muller-Steffner, [ ... ], Francis Schuber

Insight on an Arginine Synthesis Metabolon from the Tetrameric Structure of Yeast Acetylglutamate Kinase

Sergio de Cima, Fernando Gil-Ortiz, [ ... ], Vicente Rubio

Analyses of the Large Subunit Histidine-Rich Motif Expose an Alternative Proton Transfer Pathway in [NiFe] Hydrogenases

Emma Szőri-Dorogházi, Gergely Maróti, [ ... ], Kornél L. Kovács

Modulation of γ-Secretase Activity by Multiple Enzyme-Substrate Interactions: Implications in Pathogenesis of Alzheimer's Disease

Željko M. Svedružić, Katarina Popović, Ivana Smoljan, Vesna Šendula-Jengić

Structures of Helicobacter pylori Shikimate Kinase Reveal a Selective Inhibitor-Induced-Fit Mechanism

Wen-Chi Cheng, Yen-Fu Chen, [ ... ], Wen-Ching Wang

The 3′-Terminal Hexamer Sequence of Classical swine fever virus RNA Plays a Role in Negatively Regulating the IRES-Mediated Translation

Shih-Wei Huang, Meng-Yu Chan, [ ... ], Ching-Hsiu Tsai

Loss and Recovery of Mgat3 and GnT-III Mediated E-cadherin N-glycosylation Is a Mechanism Involved in Epithelial-Mesenchymal-Epithelial Transitions

Salomé S. Pinho, Patrícia Oliveira, [ ... ], Carla Oliveira

Perineuronal Nets Play a Role in Regulating Striatal Function in the Mouse

Hyunchul Lee, Catherine A. Leamey, Atomu Sawatari

Quantitative Analysis of the Effective Functional Structure in Yeast Glycolysis

Ildefonso M. De la Fuente, Jesus M. Cortes

A Catalytic Mechanism for Cysteine N-Terminal Nucleophile Hydrolases, as Revealed by Free Energy Simulations

Alessio Lodola, Davide Branduardi, [ ... ], Andrea Cavalli

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