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Enzyme structure

Structure and Function in Homodimeric Enzymes: Simulations of Cooperative and Independent Functional Motions

Stephen A. Wells, Marc W. van der Kamp, John D. McGeagh, Adrian J. Mulholland

Common and Distant Structural Characteristics of Feruloyl Esterase Families from Aspergillus oryzae

D. B. R. K. Gupta Udatha, Valeria Mapelli, Gianni Panagiotou, Lisbeth Olsson

Structural Phylogenomics Reveals Gradual Evolutionary Replacement of Abiotic Chemistries by Protein Enzymes in Purine Metabolism

Kelsey Caetano-Anollés, Gustavo Caetano-Anollés

Differential Active Site Loop Conformations Mediate Promiscuous Activities in the Lactonase SsoPox

Julien Hiblot, Guillaume Gotthard, Mikael Elias, Eric Chabriere

Modulation of γ-Secretase Activity by Multiple Enzyme-Substrate Interactions: Implications in Pathogenesis of Alzheimer's Disease

Željko M. Svedružić, Katarina Popović, Ivana Smoljan, Vesna Šendula-Jengić

A Reduction in Ribonucleotide Reductase Activity Slows Down the Chromosome Replication Fork but Does Not Change Its Localization

Ingvild Odsbu, Morigen, Kirsten Skarstad

Site-Directed Mutagenesis of a Hyperthermophilic Endoglucanase Cel12B from Thermotoga maritima Based on Rational Design

Jinfeng Zhang, Hao Shi, [ ... ], Xiangqian Li

Structures of Human DPP7 Reveal the Molecular Basis of Specific Inhibition and the Architectural Diversity of Proline-Specific Peptidases

Gustavo Arruda Bezerra, Elena Dobrovetsky, [ ... ], Sirano Dhe-Paganon

Structure of the N-Terminal Gyrase B Fragment in Complex with ADP⋅P_i Reveals Rigid-Body Motion Induced by ATP Hydrolysis

Frédéric V. Stanger, Christoph Dehio, Tilman Schirmer

Structural Features of the Regulatory ACT Domain of Phenylalanine Hydroxylase

Carla Carluccio, Franca Fraternali, [ ... ], Adriana Zagari

Designing Second Generation Anti-Alzheimer Compounds as Inhibitors of Human Acetylcholinesterase: Computational Screening of Synthetic Molecules and Dietary Phytochemicals

Hafsa Amat-ur-Rasool, Mehboob Ahmed

Insights into the Mechanism of Bovine CD38/NAD+Glycohydrolase from the X-Ray Structures of Its Michaelis Complex and Covalently-Trapped Intermediates

Pascal F. Egea, Hélène Muller-Steffner, [ ... ], Francis Schuber

Structural Differences between the Streptococcus agalactiae Housekeeping and Pilus-Specific Sortases: SrtA and SrtC1

B. Khare, V. Krishnan, [ ... ], S. V. Narayana

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