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Enzyme structure

Directed evolution to improve the catalytic efficiency of urate oxidase from Bacillus subtilis

Wenjie Li, Shouteng Xu, Biao Zhang, Yelin Zhu, Yan Hua, Xin Kong, Lianhong Sun, Jiong Hong

published 22 May 2017

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Unveiling a novel transient druggable pocket in BACE-1 through molecular simulations: Conformational analysis and binding mode of multisite inhibitors

Ornella Di Pietro, Jordi Juárez-Jiménez, Diego Muñoz-Torrero, Charles A. Laughton, F. Javier Luque

published 15 May 2017

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Model-based analysis of N-glycosylation in Chinese hamster ovary cells

Frederick J. Krambeck, Sandra V. Bennun, Mikael R. Andersen, Michael J. Betenbaugh

published 09 May 2017

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Molecular docking studies of 3-bromopyruvate and its derivatives to metabolic regulatory enzymes: Implication in designing of novel anticancer therapeutic strategies

Saveg Yadav, Shrish Kumar Pandey, Vinay Kumar Singh, Yugal Goel, Ajay Kumar, Sukh Mahendra Singh

published 02 May 2017

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Structure and function of a novel GH8 endoglucanase from the bacterial cellulose synthase complex of Raoultella ornithinolytica

Sandra Mara Naressi Scapin, Flavio Henrique Moreira Souza, Leticia Maria Zanphorlin, Thamyres Silva de Almeida, Youssef Bacila Sade, Alexander Machado Cardoso, Guilherme Luiz Pinheiro, Mario Tyago Murakami

published 27 Apr 2017

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Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis

Stefano Donini, Silvia Garavaglia, Davide M. Ferraris, Riccardo Miggiano, Shigetarou Mori, Keigo Shibayama, Menico Rizzi

published 18 Apr 2017

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Characterization of the Paenibacillus beijingensis DSM 24997 GtfD and its glucan polymer products representing a new glycoside hydrolase 70 subfamily of 4,6-α-glucanotransferase enzymes

Joana Gangoiti, Lisa Lamothe, Sander Sebastiaan van Leeuwen, Christina Vafiadi, Lubbert Dijkhuizen

published 11 Apr 2017

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Characterization and mutational analysis of a nicotinamide mononucleotide deamidase from Agrobacterium tumefaciens showing high thermal stability and catalytic efficiency

Ana Belén Martínez-Moñino, Rubén Zapata-Pérez, Antonio Ginés García-Saura, Fernando Gil-Ortiz, Manuela Pérez-Gilabert, Álvaro Sánchez-Ferrer

published 07 Apr 2017

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Streptococcus suis sortase A is Ca²⁺ independent and is inhibited by acteoside, isoquercitrin and baicalin

Fuguang Chen, Fang Xie, Baoling Yang, Chengcheng Wang, Siguo Liu, Yueling Zhang

published 20 Mar 2017

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Ligand binding at the A-cluster in full-length or truncated acetyl-CoA synthase studied by X-ray absorption spectroscopy

Peer Schrapers, Julia Ilina, Christina M. Gregg, Stefan Mebs, Jae-Hun Jeoung, Holger Dau, Holger Dobbek, Michael Haumann

published 08 Feb 2017

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Crystal Structure and Catalytic Mechanism of CouO, a Versatile C-Methyltransferase from Streptomyces rishiriensis

Tea Pavkov-Keller, Kerstin Steiner, Mario Faber, Martin Tengg, Helmut Schwab, Mandana Gruber-Khadjawi, Karl Gruber

published 02 Feb 2017

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Structural aspects of nucleotide ligand binding by a bacterial 2H phosphoesterase

Matti Myllykoski, Petri Kursula

published 31 Jan 2017

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The Role of Cysteine Residues in Catalysis of Phosphoenolpyruvate Carboxykinase from Mycobacterium tuberculosis

Iva Machová, Martin Hubálek, Martin Lepšík, Lucie Bednárová, Markéta Pazderková, Vladimír Kopecký Jr., Jan Snášel, Jiří Dostál, Iva Pichová

published 30 Jan 2017

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