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Enzyme structure

Thermal, Chemical and pH Induced Denaturation of a Multimeric β-Galactosidase Reveals Multiple Unfolding Pathways

Devesh Kishore, Suman Kundu, Arvind M. Kayastha

De Novo Enzyme Design Using Rosetta3

Florian Richter, Andrew Leaver-Fay, [ ... ], David Baker

Synergistic and Antagonistic Drug Combinations Depend on Network Topology

Ning Yin, Wenzhe Ma, [ ... ], Luhua Lai

Structural Biology of Human H3K9 Methyltransferases

Hong Wu, Jinrong Min, [ ... ], Matthieu Schapira

Crystal Structure of Human AKT1 with an Allosteric Inhibitor Reveals a New Mode of Kinase Inhibition

Wen-I Wu, Walter C. Voegtli, [ ... ], Barbara J. Brandhuber

Molecular docking studies of 3-bromopyruvate and its derivatives to metabolic regulatory enzymes: Implication in designing of novel anticancer therapeutic strategies

Saveg Yadav, Shrish Kumar Pandey, [ ... ], Sukh Mahendra Singh

Efficient CO₂-Reducing Activity of NAD-Dependent Formate Dehydrogenase from Thiobacillus sp. KNK65MA for Formate Production from CO₂ Gas

Hyunjun Choe, Jeong Chan Joo, [ ... ], Yong Hwan Kim

Structure and Reaction Mechanism of Basil Eugenol Synthase

Gordon V. Louie, Thomas J. Baiga, [ ... ], Joseph P. Noel

Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations

Hong Wu, Hong Zeng, [ ... ], Matthieu Schapira

CPORT: A Consensus Interface Predictor and Its Performance in Prediction-Driven Docking with HADDOCK

Sjoerd J. de Vries, Alexandre M. J. J. Bonvin

Enzyme-Synthesized Highly Branched Maltodextrins Have Slow Glucose Generation at the Mucosal α-Glucosidase Level and Are Slowly Digestible In Vivo

Byung-Hoo Lee, Like Yan, [ ... ], Bruce R. Hamaker

Induction of Cytoplasmic Rods and Rings Structures by Inhibition of the CTP and GTP Synthetic Pathway in Mammalian Cells

Wendy C. Carcamo, Minoru Satoh, [ ... ], Edward K. L. Chan

The Structural Stability of the Endothelial Glycocalyx after Enzymatic Removal of Glycosaminoglycans

Ye Zeng, Eno E. Ebong, Bingmei M. Fu, John M. Tarbell

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