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Enzyme structure

Thermal, Chemical and pH Induced Denaturation of a Multimeric β-Galactosidase Reveals Multiple Unfolding Pathways

Devesh Kishore, Suman Kundu, Arvind M. Kayastha

De Novo Enzyme Design Using Rosetta3

Florian Richter, Andrew Leaver-Fay, [ ... ], David Baker

Synergistic and Antagonistic Drug Combinations Depend on Network Topology

Ning Yin, Wenzhe Ma, [ ... ], Luhua Lai

Structural Biology of Human H3K9 Methyltransferases

Hong Wu, Jinrong Min, [ ... ], Matthieu Schapira

Crystal Structure of Human AKT1 with an Allosteric Inhibitor Reveals a New Mode of Kinase Inhibition

Wen-I Wu, Walter C. Voegtli, [ ... ], Barbara J. Brandhuber

Molecular docking studies of 3-bromopyruvate and its derivatives to metabolic regulatory enzymes: Implication in designing of novel anticancer therapeutic strategies

Saveg Yadav, Shrish Kumar Pandey, [ ... ], Sukh Mahendra Singh

Efficient CO₂-Reducing Activity of NAD-Dependent Formate Dehydrogenase from Thiobacillus sp. KNK65MA for Formate Production from CO₂ Gas

Hyunjun Choe, Jeong Chan Joo, [ ... ], Yong Hwan Kim

Structure and Reaction Mechanism of Basil Eugenol Synthase

Gordon V. Louie, Thomas J. Baiga, [ ... ], Joseph P. Noel

Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations

Hong Wu, Hong Zeng, [ ... ], Matthieu Schapira

CPORT: A Consensus Interface Predictor and Its Performance in Prediction-Driven Docking with HADDOCK

Sjoerd J. de Vries, Alexandre M. J. J. Bonvin

Induction of Cytoplasmic Rods and Rings Structures by Inhibition of the CTP and GTP Synthetic Pathway in Mammalian Cells

Wendy C. Carcamo, Minoru Satoh, [ ... ], Edward K. L. Chan

The Structural Stability of the Endothelial Glycocalyx after Enzymatic Removal of Glycosaminoglycans

Ye Zeng, Eno E. Ebong, Bingmei M. Fu, John M. Tarbell

Enzyme-Synthesized Highly Branched Maltodextrins Have Slow Glucose Generation at the Mucosal α-Glucosidase Level and Are Slowly Digestible In Vivo

Byung-Hoo Lee, Like Yan, [ ... ], Bruce R. Hamaker

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