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Enzyme precursors

Coagulant activity of recombinant human factor VII produced by lentiviral human F7 gene transfer in immortalized hepatocyte-like cell line

Sarai Pongjantarasatian, Praguywan Kadegasem, [ ... ], Suradej Hongeng

Selective Inhibition of Prostasin in Human Enterocytes by the Integral Membrane Kunitz-Type Serine Protease Inhibitor HAI-2

Frank Shiao, Li-Ching O. Liu, [ ... ], Chen-Yong Lin

Concerted In Vitro Trimming of Viral HLA-B27-Restricted Ligands by Human ERAP1 and ERAP2 Aminopeptidases

Elena Lorente, Alejandro Barriga, [ ... ], Daniel López

Differential Subcellular Localization Renders HAI-2 a Matriptase Inhibitor in Breast Cancer Cells but Not in Mammary Epithelial Cells

Hsiang-Hua D. Chang, Yuan Xu, [ ... ], Chen-Yong Lin

Mutation in the Pro-Peptide Region of a Cysteine Protease Leads to Altered Activity and Specificity—A Structural and Biochemical Approach

Sruti Dutta, Debi Choudhury, [ ... ], Sampa Biswas

Matriptase Complexes and Prostasin Complexes with HAI-1 and HAI-2 in Human Milk: Significant Proteolysis in Lactation

Chih-Hsin Lai, Ying-Jung J. Lai, [ ... ], Chen-Yong Lin

Uncovering the Molecular Mechanism of Actions between Pharmaceuticals and Proteins on the AD Network

Shujuan Cao, Liang Yu, [ ... ], Jishou Ruan

Towards Tricking a Pathogen’s Protease into Fighting Infection: The 3D Structure of a Stable Circularly Permuted Onconase Variant Cleavedby HIV-1 Protease

Mariona Callís, Soraya Serrano, [ ... ], Marc Ribó

Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin

Shiao-Pieng Lee, Chen-Yu Kao, [ ... ], Michael D. Johnson

Human Cancer Cells Retain Modest Levels of Enzymatically Active Matriptase Only in Extracellular Milieu following Induction of Zymogen Activation

Li-Ling Chu, Yuan Xu, [ ... ], Chen-Yong Lin

Natural Endogenous Human Matriptase and Prostasin Undergo Zymogen Activation via Independent Mechanisms in an Uncoupled Manner

Hui Chen Su, Yan A. Liang, [ ... ], Chen-Yong Lin

Structural Characterization of the Loop at the Alpha-Subunit C-Terminus of the Mixed Lineage Leukemia Protein Activating Protease Taspase1

Johannes van den Boom, Franziska Trusch, [ ... ], Peter Bayer

Overexpression of the Catalytically Impaired Taspase1^T234V or Taspase1^D233A Variants Does Not Have a Dominant Negative Effect in T(4;11) Leukemia Cells

Carolin Bier, Rouven Hecht, [ ... ], Roland H. Stauber

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