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Enzyme metabolism

Prevalence of polypharmacy and drug interactions in geriatric patients: A cross-sectional study from India

Umaima Farheen Khaiser, Rokeya Sultana, Ranajit Das, Saeed G. Alzahrani, Madhumitha Kannan, Mohammed Khairt Newigy, Mohammed Sharique Ahmed Quadri, Mujeeb Ahmed Shaikh, Farha M. Shaikh, Mohammad Fareed

published 11 Feb 2026

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Biodegradation of polyethylene terephthalate microplastics by Paenibacillus naphthalenovorans PETKKU2: Response surface optimization and genomic evidence for an alternative degradation mechanism

Aophat Choonut, Nantharat Wongfaed, Auraiwan Poolpol, Sophon Boonlue, Kitirote Wantala, Onruthai Pinyakong, Pensri Plangklang, Alissara Reungsang

published 04 Feb 2026

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Development of a CYP2D6-enhanced HepaRG cell model with improved CYP2D6 metabolic capacity

Chizuka Obara, Yohei Iizaka, Akari Mine, Yojiro Anzai, Masako Tada, Shinpei Yamaguchi

published 29 Dec 2025

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Lysine p-nitroanilide impairs cellular energetics and potentiates statin-induced cytotoxicity in RD rhabdomyosarcoma cells

Johan Alvarado-Calderón, Guillermo Juárez-Vega, Jesús Rosendo Martínez-Arellano, Hilda Sánchez-Vidal, Imelda Cecilia Zarzoza-Mendoza, David Morales-Morales, Juan Manuel Germán-Acacio, Rogelio Rodríguez-Sotres, Lilia G. Noriega, José Carlos Páez-Franco

published 04 Dec 2025

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Renal and hepatic function is preserved following inducible knockout of kynurenine pathway enzymes KMO or QPRT in adult mice

Benjamin S. Summers, Luke Milham, Sonia Bustamante, Krishan Gondal, Peggy Rentsch, Gayathri Sundaram, Michael D. Lovelace, Bryce Vissel, Bruce J. Brew

published 04 Dec 2025

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Translocation of benzo(a)pyrene reactive metabolites across human mammary epithelial cell membranes

B. Alex Merrick, Ashley M. Brooks, Julie F. Foley, Betty K. Mansfield, James K. Selkirk

published 03 Dec 2025

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Glucose priming effect on microbial intercellular metabolic flux diversity in a marine intertidal sediment

Tao Ji, Zhiao Xu, Lihong Wen, Yuxue Yang, Yue Wu, Xueqin Zhao, Ruilian Yao, Rulong Liu, Yunping Xu, Weichao Wu

published 26 Nov 2025

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Optimizing blood alcohol concentration measurement with breath alcohol meter and its preliminary application in evaluating CYP2E1 activity

Jiayi Zhang, Yingqi Hu, Ziqi Jin, Runa A, Xiaoxue Wang, Lingyu Zhang, Yongzhi Xue

published 31 Oct 2025

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Evaluating the effects of synthetic POM cycles and NAD⁺ kinase expression on fatty alcohol production in Saccharomyces cerevisiae

Bonnie A. McNeil, Charfeddine Khalifa, Anagha Krishnan, David T. Stuart

published 29 Sep 2025

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Differential regulation of long noncoding RNAs by endogenous and exogenous reactive oxygen species-generating prooxidants in NIH3T3 cells

Yoichi Kurokawa, Takashi Honda, Shingo Fujii, Yugo Narisawa, Hirotaka Ogawa, Hiroki Kawashima, Hidenori Tani

published 22 Sep 2025

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Can flavoprotein monooxygenases functionalize long-chain n-alkanes?

Raul Mireles, Arne Matthews, Robin Teufel, Lianet Noda-García

published 19 Sep 2025

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The interaction between candidate SNPs and social factors significantly influences the prevalence of alcohol use disorder in Chinese young male adults

Niu Ju, Yilu Zhao, Yuxuan Liang, Yucheng Liang

published 26 Aug 2025

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Effect of exercise intensity on redox biomarkers in healthy adults: A systematic review and meta-analysis of randomized clinical trials

Flor Isela Torres-Rojo, Liliana Aracely Enríquez-del Castillo, Susana Aidée González-Chávez, Luis Alberto Flores-Olivares, Estefanía Quintana-Mendias, Claudia Esther Carrasco-Legleu

published 20 Aug 2025

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