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Enzyme chemistry

Targeted Disruption of the PME-1 Gene Causes Loss of Demethylated PP2A and Perinatal Lethality in Mice

Silvia Ortega-Gutiérrez, Donmienne Leung, [ ... ], Benjamin F. Cravatt

Computational Systems Analysis of Dopamine Metabolism

Zhen Qi, Gary W. Miller, Eberhard O. Voit

Drug Metabolism in Human Brain: High Levels of Cytochrome P4503A43 in Brain and Metabolism of Anti-Anxiety Drug Alprazolam to Its Active Metabolite

Varsha Agarwal, Reddy P. Kommaddi, [ ... ], Vijayalakshmi Ravindranath

Pharmacokinetic Genes Do Not Influence Response or Tolerance to Citalopram in the STAR*D Sample

Eric J. Peters, Susan L. Slager, [ ... ], Steven P. Hamilton

The Impact of the Human DNA Topoisomerase II C-Terminal Domain on Activity

Emma L. Meczes, Kathryn L. Gilroy, Katherine L. West, Caroline A. Austin

Mitochondrial Lactate Dehydrogenase Is Involved in Oxidative-Energy Metabolism in Human Astrocytoma Cells (CCF-STTG1)

Joseph Lemire, Ryan J. Mailloux, Vasu D. Appanna

Functional Group and Substructure Searching as a Tool in Metabolomics

Masaaki Kotera, Andrew G. McDonald, Sinéad Boyce, Keith F. Tipton

Homology Modeling of Dissimilatory APS Reductases (AprBA) of Sulfur-Oxidizing and Sulfate-Reducing Prokaryotes

Birte Meyer, Jan Kuever

A Model for Carbohydrate Metabolism in the Diatom Phaeodactylum tricornutum Deduced from Comparative Whole Genome Analysis

Peter G. Kroth, Anthony Chiovitti, [ ... ], Chris Bowler

Structure and Reaction Mechanism of Basil Eugenol Synthase

Gordon V. Louie, Thomas J. Baiga, [ ... ], Joseph P. Noel

Metabolome Based Reaction Graphs of M. tuberculosis and M. leprae: A Comparative Network Analysis

Ketki D. Verkhedkar, Karthik Raman, Nagasuma R. Chandra, Saraswathi Vishveshwara

Is Transcriptional Regulation of Metabolic Pathways an Optimal Strategy for Fitness?

Carl Troein, Dag Ahrén, Morten Krogh, Carsten Peterson

The Tricarboxylic Acid Cycle, an Ancient Metabolic Network with a Novel Twist

Ryan J. Mailloux, Robin Bériault, [ ... ], Vasu D. Appanna

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