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Endothelial cells

Rosuvastatin protects against oxLDL-induced endothelial cell oxidative stress and attenuates atherosclerotic plaque formation in ApoE^-/- mice through the NF-κB pathway

Yichen Wu, Jiaqi Ke, Jiaxin Lv, Chaowei Cao, Chunxian Zhou, Lili Wu, Qiyang Zhou

published 20 Feb 2026

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Role of the endothelial cell apolipoprotein E receptor 2 in modulating the effects of apoE3 and apoE4 on insulin blood-brain barrier transport

Peter Thomas, Van Nguyen, Riley Weaver, Kim Hansen, Anastasia Sacharidou, William A. Banks, Chieko Mineo, Philip W. Shaul, Elizabeth M. Rhea

published 18 Feb 2026

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Meningeal lymphatic-associated brain swelling in acute stroke

Rohan Mahesh Patil, Dong Bin Back, Gen Hamanaka, Rakhi Desai, Ayumi Hayakawa, Su Jing Chan, Bum Ju Ahn, Giuseppe Pignataro, Kazuhide Hayakawa, Elga Esposito

published 12 Feb 2026

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Multi-omics analysis reveals STING activation mediates NLRP3-related pyroptosis and exacerbates myocardial ischemia-reperfusion injury

Xuehu Zhang, Aoqin Gu, Lirong Zhou, Yuru Ma, Peng Wu, Baozhen Zhu, Ru Yan, Guangzhi Cong, Xueping Ma, Shaobin Jia

published 06 Feb 2026

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The KEAP1/NRF2 axis controls LPS-induced oxidative stress, inflammasome activation and caspase-1 activity in human endothelial cells

Alba Montero-Jodra, Maria Jesús Estebán-Amo, Silvia Patricia Fernández-Martínez, César García Martínez, Miguel Ángel de la Fuente García, Adrián García-Concejo, Marta Martín-Fernández, Eduardo Tamayo, María Simarro

published 04 Feb 2026

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Single-cell RNA-seq reveals the piperlongumine is a potential drug for ischemic stroke

Jinwei Li, Xiaosi Zhu, Yan Zhang, Zixia Xu, Yurui Zhuang, Liqi Chen, Yan Cao, Chuan Chang, Yao Lv

published 23 Jan 2026

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Fluid shear stress-dependent modulation of the basal endothelial glycocalyx

Zoe Vittum, Solomon A. Mensah

published 23 Jan 2026

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Conjugation of a Cryptococcus neoformans-derived metalloprotease to antifungal-loaded PLGA nanoparticles treats neural cryptococcosis in an in vitro model

Dylan M. Lanser, Adam Turner, Noah Pacifici, Kiem Vu, Jamal Lewis, Angie Gelli

published 16 Jan 2026

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Comparative efficacy of cisternal drainage versus external ventricular drainage in severe aneurysmal subarachnoid hemorrhage

Mahamat Hamid Mahamat, Tuo Li, Jun Liu, Shusheng Zhang, Ye Miao, Zhongzhen Li, Yadan Li, Hua Yan, Guobin Zhang, Xiaoguang Tong

published 07 Jan 2026

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Preoperative and perioperative factors that predict endothelial cell loss 1 year after uncomplicated Descemet membrane endothelial keratoplasty

Jules Leterrier, Lucas Mastrangelo, Christophe Goetz, Yinka Zevering, Jean-Marc Perone

published 19 Dec 2025

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UTX/Top2β axis mediated spinal cord microvascular endothelial cells senescence exacerbates spinal cord injury

Dongliang Liu, Yudong Liu, Tianding Wu, Jianzhong Hu

published 12 Dec 2025

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Transport of CCL2 across an induced pluripotent stem cell-derived in vitro model of the human blood-brain barrier is heparan sulfate-dependent

Lindsey M. Williams, Takashi Fujimoto, Mamatha Damodarasamy, Riley R. Weaver, C. Dirk Keene, William A. Banks, May J. Reed, Michelle A. Erickson

published 11 Dec 2025

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Circular RNA FTO functions as a hsa-miR-141-3p sponge to regulate the growth and migration abilities of human retinal endothelial cells via up-regulating ZEB1

Yaoyao Chen, Renjian Hu, Enhui Li, Gaochun Li, Bing Xia, Jie Zhou

published 05 Dec 2025

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