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Elimination half-life calculation

Pharmacokinetic profiles of Moutan Cortex after single and repeated administration in a dinitrobenzene sulfonic acid-induced colitis model

Jin-Hwa Kim, Ji-Soo Jeong, Jeong-Won Kim, Eun-Hye Chung, Su-Ha Lee, Je-Won Ko, Youn-Hwan Hwang, Tae-Won Kim

published 02 Dec 2025

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Pharmacokinetic profile of oral firocoxib in the koala (Phascolarctos cinereus)

Amanda June Shapiro, Benjamin Kimble, Frances Hulst, Kimberly Vinette Herrin, Caroline Marschner, Chien-Jung Chen, Merran Govendir

published 30 Sep 2025

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Clinical safety and pharmacokinetics of a novel oral niclosamide formulation compared with marketed niclosamide chewing tablets in healthy volunteers: A three-part randomized, double-blind, placebo-controlled trial

Niklas Walther, Robert Schultz-Heienbrok, Heino Staß, Victor M. Corman, Nils C. Gassen, Marcel A. Müller, Christian Drosten, Martin Witzenrath, Hweeling Lee, Maximilian G. Posch

published 25 Feb 2025

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Platinum retention in plasma, urine, and normal colonic mucosa in cisplatin-treated testicular cancer survivors

Emilie C. H. Breekveldt, Berbel L. M. Ykema, Alwin D. R. Huitema, Jourik A. Gietema, Jos H. Beijnen, Petur Snaebjornsson, Michael Schaapveld, Flora E. van Leeuwen, Hilde Rosing, Monique E. van Leerdam, on behalf of the CATCHER study working group

published 14 Nov 2024

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Prolonging the circulatory half-life of C1 esterase inhibitor via albumin fusion

Sangavi Sivananthan, Varsha Bhakta, Negin Chaechi Tehrani, William P. Sheffield

published 23 Oct 2024

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In vivo pharmacokinetics of ginsenoside compound K mediated by gut microbiota

Ming-Si Deng, Su-tian-zi Huang, Ya-Ni Xu, Li Shao, Zheng-Guang Wang, Liang-Jian Chen, Wei-Hua Huang

published 23 Aug 2024

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Pharmacokinetics of isavuconazonium sulfate and its active metabolite isavuconazole in healthy dogs

Erin McQuinn, Jonathan P. Mochel, David Borts, Andrew S. Hanzlicek, Karin Allenspach, Jean-Sébastien Palerme

published 16 Jul 2024

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Discovery of allosteric regulators with clinical potential to stabilize alpha-L-iduronidase in mucopolysaccharidosis type I

Elena Cubero, Ana Ruano, Aida Delgado, Xavier Barril, Sara Morales, Ana Trapero, Lorenzo Leoni, Manolo Bellotto, Roberto Maj, Beatriz Calvo-Flores Guzmán, Natalia Pérez-Carmona, Ana Maria Garcia-Collazo

published 20 May 2024

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Pharmacokinetic and safety profiles of mesalazine enema in healthy Chinese subjects: A single- and multiple-dose study

Yuran Cao, Jingjing Wang, Xingyu Tang, Yan Tian, Jicheng Yu, Hong Liang, Jufang Wu, Yuancheng Chen, Guoying Cao, Jing Zhang

published 02 Feb 2024

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The pharmacokinetics and pharmacodynamics of cefquinome against Streptococcus agalactiae in a murine mastitis model

Qingwen Yang, Chenghuan Zhang, Xuesong Liu, Longfei Zhang, Kang Yong, Qian Lv, Yi Zhang, Liang Chen, Peng Zhong, Yun Liu

published 25 Jan 2023

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Efficacy of PEGylated ciliary neurotrophic factor superagonist variant in diet-induced obesity mice

Maria Rosaria Battista, Antonella Grigoletto, Tommaso Tedeschini, Antonella Cellucci, Fabrizio Colaceci, Ralph Laufer, Gianfranco Pasut, Annalise Di Marco

published 22 Mar 2022

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Conjugates for use in peptide therapeutics: A systematic review and meta-analysis

Ashan Wijesinghe, Sarika Kumari, Valerie Booth

published 08 Mar 2022

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Pharmacokinetics of a 503B outsourcing facility-produced theophylline in dogs

Jennifer M. Reinhart, Gabriela A. R. de Oliveira, Lauren Forsythe, Zhong Li

published 06 Jan 2022

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