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Drug screening

Phenotypic screening using waveform analysis of synchronized calcium oscillations in primary cortical cultures

Richi Sakaguchi, Saki Nakamura, Hiroyuki Iha, Masaki Tanaka

Deciphering the relational dynamics of AF-2 domain of PAN PPAR through drug repurposing and comparative simulations

Fouzia Gul, Nousheen Parvaiz, Syed Sikander Azam

Combining MEK and SRC inhibitors for treatment of colorectal cancer demonstrate increased efficacy in vitro but not in vivo

Fan Fan, Susmita Ghosh, [ ... ], Rajat Bhattacharya

Development and validation of a pharmaceutical assessment screening tool to prioritise patient care in a tertiary care hospital

Cheok Ee Chang, Rahela Ambaras Khan, [ ... ], Pavithira Subramaniam

Rapid generation of homogenous tumor spheroid microtissues in a scaffold-free platform for high-throughput screening of a novel combination nanomedicine

Hossein Abolhassani, Mohammad Zaer, Seyed Abbas Shojaosadati, Sameereh Hashemi-Najafabadi

Identification of therapeutic sensitivities in a spheroid drug combination screen of Neurofibromatosis Type I associated High Grade Gliomas

Jacquelyn Dougherty, Kyra Harvey, [ ... ], Thomas De Raedt

High-throughput screen in vitro identifies dasatinib as a candidate for combinatorial treatment with HER2-targeting drugs in breast cancer

Lisa Svartdal Normann, Mads Haugland Haugen, [ ... ], Gunhild Mari Mælandsmo

Riluzole for treating spasticity in patients with chronic traumatic spinal cord injury: Study protocol in the phase ib/iib adaptive multicenter randomized controlled RILUSCI trial

Maëva Cotinat, Isabelle Boquet, [ ... ], Olivier Blin

Comparing the return on investment of technologies to detect substandard and falsified amoxicillin: A Kenya case study

Colleen R. Higgins, Betty Kobia, Sachiko Ozawa

Development and validation of Tagalog versions of the Drug Abuse Screening Test-20 (DAST-20) and Stimulant Relapse Risk Scale (SRRS) for drug users in the Philippines

Takayuki Harada, Kazutaka Nomura, [ ... ], Shogo Kanamori

Phenotypic screening of 1,953 FDA-approved drugs reveals 26 hits with potential for repurposing for Peyronie’s disease

Marcus M. Ilg, Alice R. Lapthorn, David J. Ralph, Selim Cellek

Estimating the number of livebirths to Hepatitis C seropositive women in England in 2013 and 2018 using Bayesian modelling

Emily Dema, Julian Stander, [ ... ], Heather Bailey

Label-free affinity screening, design and synthesis of inhibitors targeting the Mycobacterium tuberculosis L-alanine dehydrogenase

Heung-Bok Kim, John-Paul Bacik, [ ... ], Chang-Yub Kim

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