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Drug screening

A live cell biosensor protocol for high-resolution screening of therapy-resistant cancer cells

Viral D. Oza, Colin S. Williams, Jessica S. Blackburn

Screening a library of antibacterial compounds leads to discovery of novel inhibitors for Neisseria gonorrhoeae and Chlamydia trachomatis

Abdallah S. Abdelsattar, Nader S. Abutaleb, Mohamed N. Seleem

Auranofin, identified by FDA-approved drug library screening, inhibits HBs antigen secretion via lysosomal damage

Akiyoshi Shimoda, Kazuhiro Murai, [ ... ], Tetsuo Takehara

Analysis of molecular mechanism of Chinese medicine Jinhong decoction (JHD) in synergistically treating sepsis and COVID-19 based on network pharmacology

Jinghan Fan, Yang Yang, [ ... ], Yuzhou He

Characterizing proximal risk for depressive symptoms and suicidal ideation with acute cannabis use and withdrawal among adolescents using ecological momentary assessment: Study protocol

Isabella Feibus, Marta Borrego Mahiques, [ ... ], Randi M. Schuster

An evaluation of Roluperidone as a promising repurposing candidate for Alzheimer’s Disease: A Computational Investigation

Rehnuma Tanjin, Md. Al-Amin, [ ... ], Md. Faruk Hossen

A study protocol to explore the effectiveness and implementation of mobile community outreach services for women who use drugs in Baltimore, Maryland: The SHOUT Study

Sewika Sulpe, Catherine Tomko, [ ... ], Susan G. Sherman

Computational identification of novel SIRT4 inhibitors for diabetic nephropathy using pharmacophore modeling, molecular simulations, and DFT calculations

Wenxiang He, Jianwu Chen

Integrative GWAS and RNA-Seq analysis for target identification and virtual drug screening in colorectal cancer

Qinghui Liu, Yiyang Lei, Zixuan Liu, Jiale Han

Anti-cancer compound screening identifies Aurora Kinase A inhibition as a means to favor CRISPR/Cas9 gene correction over knock-out

Danny Wilbie, Selma Eising, [ ... ], Enrico Mastrobattista

Racial disparities in urine drug screening among seizure patients in the emergency department

Gloria Ortiz-Guerrero, Maggie Logan, [ ... ], Carol M. Ulloa

Study protocol of a pilot randomized controlled trial of transcranial direct current stimulation paired with reappraisal training for treatment of cannabis use disorder

Adam M. Stryjewski, Tammy J. Chung, [ ... ], Marc N. Potenza

Computationally accelerated identification of P-glycoprotein inhibitors

Lauren A. McCormick, James W. McCormick, [ ... ], Pia D. Vogel

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