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Drug discovery

DrugReasoner: Interpretable drug approval prediction with a reasoning-augmented language model

Mohammadreza Ghaffarzadeh-Esfahani, Ali Motahharynia, Nahid Yousefian, Navid Mazrouei, Jafar Ghaisari, Yousof Gheisari

published 19 Feb 2026

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Beyond the counter: Pharmacists’ preparedness and response strategies in terrorism-related emergencies in Quetta, Pakistan

Fahad Saleem, Fazal ur Rehman Khilji, Sajjad Haider, Qaiser Iqbal, Baharudin Ibrahim, Fatiha Hana Shabaruddin, Mohammad Bashaar

published 06 Feb 2026

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Exploring patient satisfaction with community pharmacy services in the United Arab Emirates: Implications for quality improvement

Zelal Kharaba, Karem H. Alzoubi, Sayer Al-Azzam, Ahmad Al-Azayzih, Ahmad Y. Abuhelwa, Feras Jirjees, Anan Jarab, Azza Ramadan, Shoroq M. Altawalbeh, Dania Rahhal, Munazza Ahmed, Laila A. Ibrahim, Mamoon A. Aldeyab, Yassen Alfoteih, Sawsan Abuhammad

published 30 Jan 2026

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Unveiling the Plasmodium inositol (pyro)phosphate pathway: Highlighting inositol polyphosphate multikinase as a novel therapeutic target for malaria

Abigail Obuobi, Neils B. Quashie, Nancy Odurowah Duah-Quashie, Jon R. Sayers

published 10 Dec 2025

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Mass spectrometry-based metabolomics uncovers distinct metabolic signatures and potential therapeutic targets in Plasmodium knowlesi

Naphatsamon Uthailak, Sadudee Chotirat, Ammarind Anatjitsupha, Waraporn Thongyod, Phornpimon Tipthara, Jetsumon Sattabongkot, Joel Tarning, Wang Nguitragool, Onrapak Reamtong

published 13 Nov 2025

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The impact of ESG performance on corporate innovation—Empirical evidence from Chinese pharmaceutical listed companies

Liqiang Li, Su Wang, Yuwen Chen

published 04 Nov 2025

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The impact of patent activity on idiosyncratic volatility in U.S. pharmaceutical companies

Emre Atilgan, Fethiye Burcu Türkmen Ceylan, Ömer Tuğsal Doruk, Hasan Murat Ertuğrul, Ahmet Yasir Barak

published 27 Oct 2025

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Using systems biology and drug repositioning approaches to discover FDA-approved drugs candidates for endometriosis treatment

Samira Sanami, Shahrzad Aghaamoo, Sajjad Ahmad, Ali Fazli, Bahareh Mansouri, Jonas Ivan Nobre Oliveira, Mojgan Rahmanian

published 12 Sep 2025

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Genetic association of lipids characteristics and lipid lowering drug target genes with sepsis

Yu Wang, Haiyue Zhang, Yuanyuan Zhan, Zhuoran Li, Sujing Li, Yingchao Zhang, Shubin Guo

published 11 Sep 2025

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KG-MACNF: A nonlinear cross-modal fusion model for predicting drug-target interactions via multi-relational embedding and fine-grained structure

Yihan Feng, Xixin Yang, Yuanlin Guan, Jinyao Zhang, Hang Yang, Zhongyu Wang, Qi Cheng

published 09 Sep 2025

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Efficiency analysis of listed pharmaceutical companies in China: A method combining three-stage DEA with undesirable output, PCA, and tobit regression

Jiaqiang Sun, Anita Binti Rosli, Adrian Daud

published 22 Aug 2025

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Harnessing subtractive genomics for drug target identification in Streptococcus agalactiae serotype v (atcc baa-611 / 2603 v/r) strain: An in-silico approach

Ashiqur Rahman Khan Chowdhury, Farjana Yasmin Tithi, Nusrat Zahan Bhuiyan, Afsana Ferdousi Ishita, Md Mahmodul Hasan Sohel

published 21 Aug 2025

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Computationally accelerated identification of P-glycoprotein inhibitors

Lauren A. McCormick, James W. McCormick, Chanyang Park, Courtney A. Follit, John G. Wise, Pia D. Vogel

published 13 Aug 2025

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