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Drug design

Short report: Targeted analysis of whole exome sequencing data in Indian cryptogenic stroke patients

Priya Dev, Jenefer M. Blackwell, [ ... ], Abhishek Pathak

Metal coordination and enzymatic reaction of the glioma-target R132H isocitrate dehydrogenase 1: Insights by molecular simulations

Bharath Raghavan, Marco De Vivo, Paolo Carloni

Design, synthesis, and in vitro evaluation of a carbamazepine derivative with antitumor potential in a model of Acute Lymphoblastic Leukemia

Cristian Álvarez-Gómez, Angela V. Fonseca-Benítez, James Guevara-Pulido

Insights into the computer-aided drug design and discovery based on anthraquinone scaffold for cancer treatment: A systematic review

Hui Ming Chua, Said Moshawih, [ ... ], Long Chiau Ming

Insights into the computer-aided drug design and discovery based on anthraquinone scaffold for cancer treatment: A protocol for systematic review

Hui Ming Chua, Said Moshawih, [ ... ], Nurolaini Kifli

Role of ADAMTS13, VWF and F8 genes in deep vein thrombosis

Maria Teresa Pagliari, Andrea Cairo, [ ... ], Flora Peyvandi

Prioritization of candidate genes for a South African family with Parkinson’s disease using in-silico tools

Boiketlo Sebate, Katelyn Cuttler, [ ... ], Soraya Bardien

Novel genetic variants of inborn errors of immunity

Farida Almarzooqi, Abdul-Kader Souid, Ranjit Vijayan, Suleiman Al-Hammadi

SVAD: A genetic database curates non-ischemic sudden cardiac death-associated variants

Wei-Chih Huang, Hsin-Tzu Huang, [ ... ], Hsien-Da Huang

MISTIC: A prediction tool to reveal disease-relevant deleterious missense variants

Kirsley Chennen, Thomas Weber, [ ... ], Olivier Poch

Clinical interpretation of variants identified in RNU4ATAC, a non-coding spliceosomal gene

Clara Benoit-Pilven, Alicia Besson, [ ... ], Sylvie Mazoyer

Human exome and mouse embryonic expression data implicate ZFHX3, TRPS1, and CHD7 in human esophageal atresia

Rong Zhang, Jan Gehlen, [ ... ], Heiko Reutter

Phenogenon: Gene to phenotype associations for rare genetic diseases

Nikolas Pontikos, Cian Murphy, [ ... ], UK Inherited Retinal Dystrophy Consortium, Phenopolis Consortium

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