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Drug administration

A six-hour time series of the acute effects of ingested cannabis intoxication on a battery of cognitive-motor tasks

Paige V. Copeland, Quinn Malone, Brian H. Dalton, Chris J. McNeil

published 13 Aug 2026

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Pharmacokinetic model selection for infliximab based on inflammatory bowel disease phenotype and severity: Toward model-informed precision dosing

Ana Homšek Ilić, Marija Jovanović, Srđan Marković, Sandra Vezmar Kovačević, Tamara Knežević Ivanovski, Đorđe Kralj, Petar Svorcan, Katarina Vučićević

published 24 Jul 2026

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Decision tree model to assess consequences and costs associated with therapy administration pathways for patients with HER2+ breast cancer in Italian oncological centers

Giorgia Gribaudo, Carla Fornari, Ippazio Cosimo Antonazzo, Daniele Generali, Carlo Carnaghi, Alessandro Galimberti, Patrizia Nardulli, Monica Calamai, Davide Marchesini, Lorenzo Giovanni Mantovani, Paolo Angelo Cortesi

published 24 Jul 2026

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Optimal design of dose and drug pharmacokinetic characteristics to achieve the desired pharmacodynamic profile in repeated drug dosing

Martin Dodek, Zuzana Vitková, Anton Vitko, Eva Miklovičová

published 22 Jul 2026

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A phase III double-blind, placebo-controlled, randomized withdrawal trial of 5‑aminolevulinic acid hydrochloride with sodium ferrous citrate for efficacy and safety in patients diagnosed as Leigh syndrome

Akira Ohtake, Yuichi Abe, Kei Murayama, Hideaki Shiraishi, Hitoshi Osaka, Satoko Kumada, Tetsuya Ito, Hidehito Kondo, Yusuke Hamada, Sayaka Suzuki-Ajihara, Masato Arao, Yuki Ueda, Kohei Nagai, Keiko Ichimoto, Ayako Matsunaga, Hirofumi Kashii, Yoko Nakajima, Hitoshi Nakagawa, Shunichi Kurose, Kaori Fukuda, Kiwamu Takahashi, Mitsugu Yamauchi, Motowo Nakajima

published 17 Jul 2026

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Design and validation of a key performance indicator dashboard for equity in community and retail pharmacy services in Pakistan

Muhammad Hammad, Rasikh Arif, Ali Zeb Khan, Ali Nasir

published 10 Jul 2026

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Pharmacokinetic interactions between three SGLT2 inhibitors and telmisartan: A focus on empagliflozin, ertugliflozin, and henagliflozin

Xin Zhou, Yanru Deng, Caihui Guo, Ying Li, Yuhao Fu, Zhi Wang, Zhanjun Dong

published 22 Jun 2026

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Advancements in fire-related toxic gas detection and prophylactic strategies: A focus on cyanide concentration analysis and antidote efficacy in controlled smoke inhalation models

Jowy Tani, Jia-Long Chen, Wei-Chuan Liao, Chia-Hung Chen, Chau-Hui Wang, Tzu-hui Sun, Yow-Ling Shiue, Jin-Wu Tsai

published 15 Jun 2026

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Dynamic effects of China’s national volume-based procurement on generic drug consistency evaluation: An interrupted time series analysis

Xianli Ge, Xiaodong Liu, Weiyu Tian, Jing Peng, Mingyue Zhao, Yu Fang

published 10 Jun 2026

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Prevalence of re-laparotomy and its risk factors in patients who underwent gastrointestinal procedure at Referral Hospital in Ethiopia

Kumlachew Geta, Amsalu Molla, Yonas Kassaw, Simegnew Kibret, Metages Hunie, Kaletsidk Dessalegn, Diriba Teshome, Belayneh Dessie, Keder Essa, Efrem Fenta

published 29 May 2026

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Machine learning-based unified models for predicting drug clearance from pharmacokinetic animal and study design variables

Remya Ampadi Ramachandran, Lisa A. Tell, Melissa A. Mercer, Xuan Xu, Nuwan Indika Millagaha Gedara, Maaike Ottoline Clapham, Zhoumeng Lin, Jim E. Riviere, Majid Jaberi-Douraki

published 06 May 2026

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Evaluation and enhancement of suspected opioid overdose definitions in emergency medical services data using machine learning with natural language processing

Peter Rock, Svetla Slavova, Sharon L. Walsh, Julia Martin, Daniel R. Harris

published 28 Apr 2026

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Evaluation of therapeutic efficacy of baloxavir marboxil against high pathogenicity avian influenza virus infection in duck model

Yo Shimazu, Norikazu Isoda, Takahiro Hiono, Yik Lim Hew, Daiki Kobayashi, Misato Shibazaki, Bao Linh Nguyen, Tatsuru Morita, Ryo Daniel Obara, Mariko Miki, Hiromi Osaki, Takao Shishido, Yoshinori Ikenaka, Yoshihiro Sakoda

published 15 Apr 2026

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