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Dose prediction methods

Effectiveness of Antenatal Clinics to Deliver Intermittent Preventive Treatment and Insecticide Treated Nets for the Control of Malaria in Pregnancy in Mali: A Household Survey

Jenny Hill, Kassoum Kayentao, Mahamoudou Touré, Sory Diarwara, Jane Bruce, James Smedley, Ogobara K. Doumbo, Feiko O. ter. Kuile, Jayne Webster

published 20 Mar 2014

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The Association between Contrast Dose and Renal Complications Post PCI across the Continuum of Procedural Estimated Risk

Judith Kooiman, Milan Seth, David Share, Simon Dixon, Hitinder S. Gurm

published 13 Mar 2014

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Using Multivariate Regression Model with Least Absolute Shrinkage and Selection Operator (LASSO) to Predict the Incidence of Xerostomia after Intensity-Modulated Radiotherapy for Head and Neck Cancer

Tsair-Fwu Lee, Pei-Ju Chao, Hui-Min Ting, Liyun Chang, Yu-Jie Huang, Jia-Ming Wu, Hung-Yu Wang, Mong-Fong Horng, Chun-Ming Chang, Jen-Hong Lan, Ya-Yu Huang, Fu-Min Fang, Stephen Wan Leung

published 28 Feb 2014

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A Novel Toxicokinetic Modeling of Cypermethrin and Permethrin and Their Metabolites in Humans for Dose Reconstruction from Biomarker Data

Jonathan Côté, Yvette Bonvalot, Gaétan Carrier, Caroline Lapointe, Uwe Fuhr, Dorota Tomalik-Scharte, Bertil Wachall, Michèle Bouchard

published 26 Feb 2014

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Extending the Applicability of the Dose Addition Model to the Assessment of Chemical Mixtures of Partial Agonists by Using a Novel Toxic Unit Extrapolation Method

Martin Scholze, Elisabete Silva, Andreas Kortenkamp

published 12 Feb 2014

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Development and Validation of a Gene Expression Score That Predicts Response to Fulvestrant in Breast Cancer Patients

Steen Knudsen, Thomas Jensen, Anker Hansen, Wiktor Mazin, Justin Lindemann, Irene Kuter, Naomi Laing, Elizabeth Anderson

published 05 Feb 2014

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Pharmacogenetic-Based Efavirenz Dose Modification: Suggestions for an African Population and the Different CYP2B6 Genotypes

Jackson K. Mukonzo, Joel S. Owen, Jasper Ogwal-Okeng, Ronald B. Kuteesa, Sarah Nanzigu, Nelson Sewankambo, Lehana Thabane, Lars L. Gustafsson, Colin Ross, Eleni Aklillu

published 31 Jan 2014

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The Biological Effect of Large Single Doses: A Possible Role for Non-Targeted Effects in Cell Inactivation

Marlon R. Veldwijk, Bo Zhang, Frederik Wenz, Carsten Herskind

published 22 Jan 2014

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Population Pharmacodynamic Modeling and Simulation of the Respiratory Effect of Acetazolamide in Decompensated COPD Patients

Nicholas Heming, Saïk Urien, Virginie Fulda, Ferhat Meziani, Arnaud Gacouin, Marc Clavel, Benjamin Planquette, Christophe Faisy

published 17 Jan 2014

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Strong Relationship between Oral Dose and Tenofovir Hair Levels in a Randomized Trial: Hair as a Potential Adherence Measure for Pre-Exposure Prophylaxis (PrEP)

Albert Y. Liu, Qiyun Yang, Yong Huang, Peter Bacchetti, Peter L. Anderson, Chengshi Jin, Kathy Goggin, Kristefer Stojanovski, Robert Grant, Susan P. Buchbinder, Ruth M. Greenblatt, Monica Gandhi

published 08 Jan 2014

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Anti-Prion Activity of a Panel of Aromatic Chemical Compounds: In Vitro and In Silico Approaches

Natalia C. Ferreira, Icaro A. Marques, Wesley A. Conceição, Bruno Macedo, Clarice S. Machado, Alessandra Mascarello, Louise Domeneghini Chiaradia-Delatorre, Rosendo Augusto Yunes, Ricardo José Nunes, Andrew G. Hughson, Lynne D. Raymond, Pedro G. Pascutti, Byron Caughey, Yraima Cordeiro

published 06 Jan 2014

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Exploiting the Synergy between Carboplatin and ABT-737 in the Treatment of Ovarian Carcinomas

Harsh Vardhan Jain, Alan Richardson, Michael Meyer-Hermann, Helen M. Byrne

published 06 Jan 2014

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A Model of Photon Cell Killing Based on the Spatio-Temporal Clustering of DNA Damage in Higher Order Chromatin Structures

Lisa Herr, Thomas Friedrich, Marco Durante, Michael Scholz

published 02 Jan 2014

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