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DNA vaccination

Evaluation of immunogenicity-induced DNA vaccines against different SARS-CoV-2 variants

Se Eun Kim, So Hee Park, Woo-Jung Park, Gayeong Kim, Seo Yeon Kim, Hyeran Won, Yun-Ho Hwang, Heeji Lim, Hyeon Guk Kim, You-Jin Kim, Dokeun Kim, Jung-Ah Lee

published 07 Dec 2023

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Humoral immunogenicity of a Coronavirus Disease 2019 (COVID-19) DNA vaccine in rhesus macaques (Macaca mulatta) delivered using needle-free jet injection

Alexandra Jay, Steven A. Kwilas, Matthew Josleyn, Keersten Ricks, Jay W. Hooper

published 31 May 2023

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The DNA co-vaccination using Sm antigen and IL-10 as prophylactic experimental therapy ameliorates nephritis in a model of lupus induced by pristane

Beatriz Teresita Martín-Márquez, Minoru Satoh, Rogelio Hernández-Pando, Erika Aurora Martínez-García, Marcelo Heron Petri, Flavio Sandoval-García, Oscar Pizano-Martinez, Trinidad García-Iglesias, Fernanda Isadora Corona-Meraz, Monica Vázquez-Del Mercado

published 27 Oct 2021

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DNA vaccine candidate encoding SARS-CoV-2 spike proteins elicited potent humoral and Th1 cell-mediated immune responses in mice

Eakachai Prompetchara, Chutitorn Ketloy, Kittipan Tharakhet, Papatsara Kaewpang, Supranee Buranapraditkun, Teerasit Techawiwattanaboon, Suwitra Sathean-anan-kun, Patrawadee Pitakpolrat, Supaporn Watcharaplueksadee, Supaporn Phumiamorn, Wassana Wijagkanalan, Kanitha Patarakul, Tanapat Palaga, Kiat Ruxrungtham

published 22 Mar 2021

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Acceptability and tolerability of repeated intramuscular electroporation of Multi-antigenic HIV (HIVMAG) DNA vaccine among healthy African participants in a phase 1 randomized controlled trial

Juliet Mpendo, Gaudensia Mutua, Annet Nanvubya, Omu Anzala, Julien Nyombayire, Etienne Karita, Len Dally, Drew Hannaman, Matt Price, Patricia E. Fast, Frances Priddy, Huub C. Gelderblom, Nancy K. Hills

published 29 May 2020

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Therapeutic DNA vaccine attenuates itching and allergic inflammation in mice with established biting midge allergy

Mey Fann Lee, Yi-Hsing Chen, Pei-Pong Song, Tzu-Mei Lin

published 23 Apr 2020

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Safety and immunogenicity of investigational seasonal influenza hemagglutinin DNA vaccine followed by trivalent inactivated vaccine administered intradermally or intramuscularly in healthy adults: An open-label randomized phase 1 clinical trial

Cristina Carter, Katherine V. Houser, Galina V. Yamshchikov, Abbie R. Bellamy, Jeanine May, Mary E. Enama, Uzma Sarwar, Brenda Larkin, Robert T. Bailer, Richard Koup, Grace L. Chen, Shital M. Patel, Patricia Winokur, Robert Belshe, Cornelia L. Dekker, Barney S. Graham, Julie E. Ledgerwood, the VRC 703 study team

published 18 Sep 2019

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Intradermal DNA vaccination combined with dual CTLA-4 and PD-1 blockade provides robust tumor immunity in murine melanoma

Spela Kos, Alessandra Lopes, Veronique Preat, Maja Cemazar, Ursa Lampreht Tratar, Bernard Ucakar, Kevin Vanvarenberg, Gregor Sersa, Gaelle Vandermeulen

published 31 May 2019

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Co-expression of IL-15 enhances anti-neuroblastoma effectivity of a tyrosine hydroxylase-directed DNA vaccination in mice

Madlen Marx, Maxi Zumpe, Sascha Troschke-Meurer, Diana Shah, Holger N. Lode, Nikolai Siebert

published 19 Nov 2018

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DNA vaccine priming for seasonal influenza vaccine in children and adolescents 6 to 17 years of age: A phase 1 randomized clinical trial

Katherine V. Houser, Galina V. Yamshchikov, Abbie R. Bellamy, Jeanine May, Mary E. Enama, Uzma Sarwar, Brenda Larkin, Robert T. Bailer, Richard Koup, Myeisha Paskel, Kanta Subbarao, Edwin Anderson, David I. Bernstein, Buddy Creech, Harry Keyserling, Paul Spearman, Peter F. Wright, Barney S. Graham, Julie E. Ledgerwood, the VRC 702 study team

published 02 Nov 2018

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Transcriptome analyses of Atlantic salmon muscle genes induced by a DNA vaccine against salmonid alphavirus, the causative agent of salmon pancreas disease (PD)

Mehrdad Sobhkhez, Aleksei Krasnov, Børre Robertsen

published 01 Oct 2018

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Safety and tolerability of HIV-1 multiantigen pDNA vaccine given with IL-12 plasmid DNA via electroporation, boosted with a recombinant vesicular stomatitis virus HIV Gag vaccine in healthy volunteers in a randomized, controlled clinical trial

Marnie L. Elizaga, Shuying S. Li, Nidhi K. Kochar, Gregory J. Wilson, Mary A. Allen, Hong Van N. Tieu, Ian Frank, Magdalena E. Sobieszczyk, Kristen W. Cohen, Brittany Sanchez, Theresa E. Latham, David K. Clarke, Michael A. Egan, John H. Eldridge, Drew Hannaman, Rong Xu, Ayuko Ota-Setlik, M. Juliana McElrath, Christine Mhorag Hay, on behalf of the NIAID HIV Vaccine Trials Network (HVTN) 087 Study Team

published 20 Sep 2018

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Tolerogenic β2-glycoprotein I DNA vaccine and FK506 as an adjuvant attenuates experimental obstetric antiphospholipid syndrome

Ya-Hsuan Chao, Der-Yuan Chen, Joung-Liang Lan, Kuo-Tung Tang, Chi-Chien Lin

published 12 Jun 2018

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