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DNA fragmentation

Evaluation of KRAS, NRAS and BRAF mutations detection in plasma using an automated system for patients with metastatic colorectal cancer

Claire Franczak, Andréa Witz, Karen Geoffroy, Jessica Demange, Marie Rouyer, Marie Husson, Vincent Massard, Céline Gavoille, Aurélien Lambert, Pauline Gilson, Nicolas Gambier, Julien Scala-Bertola, Jean-Louis Merlin, Alexandre Harlé

published 15 Jan 2020

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Cell-free DNA donor fraction analysis in pediatric and adult heart transplant patients by multiplexed allele-specific quantitative PCR: Validation of a rapid and highly sensitive clinical test for stratification of rejection probability

Paula E. North, Emily Ziegler, Donna K. Mahnke, Karl D. Stamm, Angela Thomm, Paul Daft, Mary Goetsch, Huan ling Liang, Maria Angeles Baker, Adam Vepraskas, Chris Rosenau, Mahua Dasgupta, Pippa Simpson, Michael E. Mitchell, Aoy Tomita-Mitchell

published 13 Jan 2020

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Sequencing artifacts derived from a library preparation method using enzymatic fragmentation

Norio Tanaka, Akihisa Takahara, Taichi Hagio, Rika Nishiko, Junko Kanayama, Osamu Gotoh, Seiichi Mori

published 03 Jan 2020

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Combination treatment of berberine and solid lipid curcumin particles increased cell death and inhibited PI3K/Akt/mTOR pathway of human cultured glioblastoma cells more effectively than did individual treatments

Panchanan Maiti, Alexandra Plemmons, Gary L. Dunbar

published 16 Dec 2019

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Elucidation of a non-thermal mechanism for DNA/RNA fragmentation and protein degradation when using Lyse-It

Tonya M. Santaus, Ken Greenberg, Prabhdeep Suri, Chris D. Geddes

published 02 Dec 2019

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Circulating cell-free DNA from plasma undergoes less fragmentation during bisulfite treatment than genomic DNA due to low molecular weight

Bonnita Werner, Nicole Laurencia Yuwono, Claire Henry, Kate Gunther, Robert William Rapkins, Caroline Elizabeth Ford, Kristina Warton

published 25 Oct 2019

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Novel chemotherapeutic agent, FND-4b, activates AMPK and inhibits colorectal cancer cell proliferation

Heather F. Sinner, Jeremy Johnson, Piotr G. Rychahou, David S. Watt, Yekaterina Y. Zaytseva, Chunming Liu, B. Mark Evers

published 24 Oct 2019

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Automated smartphone-based system for measuring sperm viability, DNA fragmentation, and hyaluronic binding assay score

Irene Dimitriadis, Charles L. Bormann, Manoj Kumar Kanakasabapathy, Prudhvi Thirumalaraju, Hemanth Kandula, Vinish Yogesh, Neeraj Gudipati, Vignesh Natarajan, John C. Petrozza, Hadi Shafiee

published 13 Mar 2019

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Integrated routine workflow using next-generation sequencing and a fully-automated platform for the detection of KRAS, NRAS and BRAF mutations in formalin-fixed paraffin embedded samples with poor DNA quality in patients with colorectal carcinoma

Claire Franczak, Ludovic Dubouis, Pauline Gilson, Marie Husson, Marie Rouyer, Jessica Demange, Agnès Leroux, Jean-Louis Merlin, Alexandre Harlé

published 27 Feb 2019

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The effects and mechanism of peiminine-induced apoptosis in human hepatocellular carcinoma HepG2 cells

Xu Chao, Guoquan Wang, Yuping Tang, Changhu Dong, Hong Li, Bin Wang, Jieqiong Wu, Jiarong Zhao

published 07 Jan 2019

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Influence of warming and reanimation conditions on seminiferous tubule morphology, mitochondrial activity, and cell composition of vitrified testicular tissues in the domestic cat model

David Baruc Cruvinel Lima, Lúcia Daniel Machado da Silva, Pierre Comizzoli

published 08 Nov 2018

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Pyronaridine exerts potent cytotoxicity on human breast and hematological cancer cells through induction of apoptosis

Paulina J. Villanueva, Alberto Martinez, Sarah T. Baca, Rebecca E. DeJesus, Manuel Larragoity, Lisett Contreras, Denisse A. Gutierrez, Armando Varela-Ramirez, Renato J. Aguilera

published 05 Nov 2018

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Rapid sample preparation with Lyse-It® for Listeria monocytogenes and Vibrio cholerae

Tonya M. Santaus, Shan Li, Paula Ladd, Amanda Harvey, Shannon Cole, O. Colin Stine, Chris D. Geddes

published 25 Jul 2018

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