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DNA damage

p53 oligomerization status as an indicator of sensitivity of p53-wildtype neuroblastomas to the combination of DNA damaging agent and Chk1 inhibitor

Aime A. Levesque, Rebecca M. Pappalardo, Pawan Puli, Laura A. Enzor, Clara Angeles

published 10 Feb 2022

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HPV16 E1 dysregulated cellular genes involved in cell proliferation and host DNA damage: A possible role in cervical carcinogenesis

Fern Baedyananda, Arkom Chaiwongkot, Shankar Varadarajan, Parvapan Bhattarakosol

published 30 Dec 2021

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Senotherapeutic-like effect of Silybum marianum flower extract revealed on human skin cells

Jieun Woo, Seoungwoo Shin, Eunae Cho, Dehun Ryu, David Garandeau, Hanane Chajra, Mathilde Fréchet, Deokhoon Park, Eunsun Jung

published 16 Dec 2021

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New insight on some selected nanoparticles as an effective adsorbent toward diminishing the health risk of deltamethrin contaminated water

Samar M. Ibrahium, Ahmed A. Farghali, Rehab Mahmoud, Ahmed A. Wahba, Saeed El-Ashram, Hesham A. Mahran, Shawky M. Aboelhadid

published 04 Nov 2021

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PKI-587 enhances radiosensitization of hepatocellular carcinoma by inhibiting the PI3K/AKT/mTOR pathways and DNA damage repair

Yinghai Xie, Changwei Liu, Yinci Zhang, Amin Li, Chong Sun, Rui Li, Yingru Xing, Minghong Shi, Qi Wang

published 19 Oct 2021

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C. elegans genome-wide analysis reveals DNA repair pathways that act cooperatively to preserve genome integrity upon ionizing radiation

Bettina Meier, Nadezda V. Volkova, Bin Wang, Víctor González-Huici, Simone Bertolini, Peter J. Campbell, Moritz Gerstung, Anton Gartner

published 06 Oct 2021

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Induction of mitochondria mediated apoptosis in human ovarian cancer cells by folic acid coated tin oxide nanoparticles

Demiana H. Hanna, Gamal R. Saad

published 01 Oct 2021

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Mild phenotype of knockouts of the major apurinic/apyrimidinic endonuclease APEX1 in a non-cancer human cell line

Daria V. Kim, Liliya M. Kulishova, Natalia A. Torgasheva, Vasily S. Melentyev, Grigory L. Dianov, Sergey P. Medvedev, Suren M. Zakian, Dmitry O. Zharkov

published 16 Sep 2021

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Uncovering the genomic and metagenomic research potential in old ethanol-preserved snakes

Claus M. Zacho, Martina A. Bager, Ashot Margaryan, Peter Gravlund, Anders Galatius, Arne R. Rasmussen, Morten E. Allentoft

published 23 Aug 2021

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MT1-MMP-dependent ECM processing regulates laminB1 stability and mediates replication fork restart

Varsha Thakur, Juliano Tiburcio de Freitas, Yuan Li, Keman Zhang, Alyssa Savadelis, Barbara Bedogni

published 08 Jul 2021

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Effects of low-dose X-ray medical diagnostics on female gonads: Insights from large animal oocytes and human ovaries as complementary models

Nicola Antonio Martino, Rossella Vicenti, Maria Macciocca, Renato Seracchioli, Giuseppina Marzano, Antonella Mastrorocco, Giovanni Michele Lacalandra, Michele Tomaiuolo, Giuliana Marchesani, Eugenio Antonio Chiaravalle, Francesca Gioia Klinger, Serena Marcozzi, Raffaella Fabbri, Maria Elena Dell’Aquila

published 24 Jun 2021

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CHD4 regulates platinum sensitivity through MDR1 expression in ovarian cancer: A potential role of CHD4 inhibition as a combination therapy with platinum agents

Yoshiko Oyama, Shogo Shigeta, Hideki Tokunaga, Keita Tsuji, Masumi Ishibashi, Yusuke Shibuya, Muneaki Shimada, Jun Yasuda, Nobuo Yaegashi

published 23 Jun 2021

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Cytoplasmic RRM1 activation as an acute response to gemcitabine treatment is involved in drug resistance of pancreatic cancer cells

Tomotaka Kato, Hiroaki Ono, Mikiya Fujii, Keiichi Akahoshi, Toshiro Ogura, Kosuke Ogawa, Daisuke Ban, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe

published 10 Jun 2021

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