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DNA damage

Transcriptome profiling of human col\onic cells exposed to the gut pathobiont Streptococcus gallolyticus subsp. gallolyticus

Ewa Pasquereau-Kotula, Laurence du Merle, Odile Sismeiro, Natalia Pietrosemoli, Hugo Varet, Rachel Legendre, Patrick Trieu-Cuot, Shaynoor Dramsi

published 30 Nov 2023

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Loss of Aspm causes increased apoptosis of developing neural cells during mouse cerebral corticogenesis

Madoka Tonosaki, Akira Fujimori, Takeshi Yaoi, Kyoko Itoh

published 29 Nov 2023

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Cas9 is mostly orthogonal to human systems of DNA break sensing and repair

Ekaterina A. Maltseva, Inna A. Vasil’eva, Nina A. Moor, Daria V. Kim, Nadezhda S. Dyrkheeva, Mikhail M. Kutuzov, Ivan P. Vokhtantsev, Lilya M. Kulishova, Dmitry O. Zharkov, Olga I. Lavrik

published 29 Nov 2023

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Sensing chemical-induced genotoxicity and oxidative stress via yeast-based reporter assays using NanoLuc luciferase

Minami Shichinohe, Shun Ohkawa, Yuu Hirose, Toshihiko Eki

published 22 Nov 2023

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Preclinical safety evaluation of continuous UV-A lighting in an operative setting

Rachael Guenter, Rui Zheng-Pywell, Brendon Herring, Madisen Murphy, Jeremy Foote, Kevin Benner, J. Bart Rose

published 17 Nov 2023

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Bioenergetic function is decreased in peripheral blood mononuclear cells of veterans with Gulf War Illness

Joel N. Meyer, William K. Pan, Ian T. Ryde, Thomas Alexander, Jacquelyn C. Klein-Adams, Duncan S. Ndirangu, Michael J. Falvo

published 01 Nov 2023

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Assessing radiation dosimetry for microorganisms in naturally radioactive mineral springs using GATE and Geant4-DNA Monte Carlo simulations

Sofia Kolovi, Giovanna-Rosa Fois, Sarra Lanouar, Patrick Chardon, Didier Miallier, Lory-Anne Baker, Céline Bailly, Aude Beauger, David G. Biron, Karine David, Gilles Montavon, Thierry Pilleyre, Benoît Schoefs, Vincent Breton, Lydia Maigne, with the TIRAMISU Collaboration

published 12 Oct 2023

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Nanomaterial genotoxicity evaluation using the high-throughput p53-binding protein 1 (53BP1) assay

Maelle Fontaine, Eline Bartolami, Marion Prono, David Béal, Magda Blosi, Anna L. Costa, Costanza Ravagli, Giovanni Baldi, Simone Sprio, Anna Tampieri, Ivana Fenoglio, Lang Tran, Bengt Fadeel, Marie Carriere

published 15 Sep 2023

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Helicase-like transcription factor (Hltf)-deletion activates Hmgb1-Rage axis and granzyme A-mediated killing of pancreatic β cells resulting in neonatal lethality

Gurvinder Kaur, Rebecca A. Helmer, Dalia Martinez-Marin, Souad R. Sennoune, Rachel L. Washburn, Raul Martinez-Zaguilan, Jannette M. Dufour, Beverly S. Chilton

published 25 Aug 2023

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The CST complex facilitates cell survival under oxidative genotoxic stress

Tomohiko Hara, Hidenori Nakaoka, Tomoicihiro Miyoshi, Fuyuki Ishikawa

published 17 Aug 2023

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PHRF1 promotes the class switch recombination of IgA in CH12F3-2A cells

Jin-Yu Lee, Nai-Lin Chou, Ya-Ru Yu, Hsin-An Shih, Hung-Wei Lin, Chine-Kuo Lee, Mau-Sun Chang

published 04 Aug 2023

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The order of sequential exposure of U2OS cells to gamma and alpha radiation influences the formation and decay dynamics of NBS1 foci

Adrianna Tartas, Lovisa Lundholm, Harry Scherthan, Andrzej Wojcik, Beata Brzozowska

published 12 Jun 2023

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Effects of acute low-moderate dose ionizing radiation to human brain organoids

Foluwasomi A. Oyefeso, Gabriela Goldberg, Nana Yaa P. S. Opoku, Marcelo Vazquez, Antonella Bertucci, Zhong Chen, Charles Wang, Alysson R. Muotri, Michael J. Pecaut

published 31 May 2023

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