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DNA damage

Relief of endoplasmic reticulum stress enhances DNA damage repair and improves development of pre-implantation embryos

Naomi Dicks, Rodrigo C. Bohrer, [ ... ], Vilceu Bordignon

Characterization of the deubiquitination activity and substrate specificity of the chicken ubiquitin-specific protease 1/USP associated factor 1 complex

Hainan Zheng, Mengyun Wang, [ ... ], Yongxing Ai

Biochemical characterization of Borrelia burgdorferi’s RecA protein

Shu Hui Huang, Madison A. Hart, [ ... ], Kerri Kobryn

Hypomethylated Fgf3 is a potential biomarker for early detection of oral cancer in mice treated with the tobacco carcinogen dibenzo[def,p]chrysene

Yuan-Wan Sun, Kun-Ming Chen, [ ... ], Karam El-Bayoumy

A small molecule drug promoting miRNA processing induces alternative splicing of MdmX transcript and rescues p53 activity in human cancer cells overexpressing MdmX protein

Georgios Valianatos, Barbora Valcikova, [ ... ], Stjepan Uldrijan

TLR9 stimulation of B-cells induces transcription of p53 and prevents spontaneous and irradiation-induced cell death independent of DNA damage responses. Implications for Common variable immunodeficiency

Kristine Lillebø Holm, Randi Gussgard Syljuåsen, [ ... ], Heidi Kiil Blomhoff

MicroRNA-16 feedback loop with p53 and Wip1 can regulate cell fate determination between apoptosis and senescence in DNA damage response

Maria Vitória C. Issler, José Carlos M. Mombach

The histone variant macroH2A confers functional robustness to the intestinal stem cell compartment

Ryan James Cedeno, Angela Nakauka-Ddamba, [ ... ], Christopher Joachim Lengner

Selective cytotoxicity of the anti-diabetic drug, metformin, in glucose-deprived chicken DT40 cells

Kei Kadoda, Takahito Moriwaki, [ ... ], Keizo Tano

Role of mitochondrial DNA damage and dysfunction in veterans with Gulf War Illness

Yang Chen, Joel N. Meyer, [ ... ], Michael J. Falvo

Alkylation induced cerebellar degeneration dependent on Aag and Parp1 does not occur via previously established cell death mechanisms

Carrie M. Margulies, Isaac Alexander Chaim, [ ... ], Leona D. Samson

DNA strand breaks and TDP-43 mislocation are absent in the murine hSOD1G93A model of amyotrophic lateral sclerosis in vivo and in vitro

Diane Penndorf, Vedrana Tadić, [ ... ], Alexandra Kretz

Novel histone deacetylase inhibitor AR-42 exhibits antitumor activity in pancreatic cancer cells by affecting multiple biochemical pathways

Yi-Jin Chen, Wen-Hung Wang, [ ... ], Wan-Chi Tsai

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