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DNA binding assay

Characterization of p53 p.T253I as a pathogenic mutation underlying Li-Fraumeni Syndrome

Nathaniel C. Holcomb, Amanda M. Harrington, Hong Pu, Berina Halilovic, Nathan R. Shelman, Shulin Zhang, Catherine Sears, Terra Armstrong, Brent Shelton, Lauren Corum, John A. D'Orazio

published 05 Dec 2025

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Direct activation of HSF1 by macromolecular crowding and misfolded proteins

Oliver Simoncik, Vlastimil Tichy, Michal Durech, Lenka Hernychova, Filip Trcka, Lukas Uhrik, Miroslav Bardelcik, Philip J. Coates, Borivoj Vojtesek, Petr Muller

published 04 Nov 2024

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Epigallocatechin gallate regulates the myeloid-specific transcription factor PU.1 in macrophages

Manjula Karpurapu, Kavita Kumari Kakarala, Sangwoon Chung, Yunjuan Nie, Amritendu Koley, Patrick Dougherty, John W. Christman

published 25 Apr 2024

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Single molecule studies characterize the kinetic mechanism of tetrameric p53 binding to different native response elements

Johannes P. Suwita, Calvin K. Voong, Elina Ly, James A. Goodrich, Jennifer F. Kugel

published 15 Aug 2023

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DNA binding by the Rad9A subunit of the Rad9-Rad1-Hus1 complex

Bor-Jang Hwang, Rex Gonzales, Sage Corzine, Emilee Stenson, Lakshmi Pidugu, A-Lien Lu

published 08 Aug 2022

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POT1 stability and binding measured by fluorescence thermal shift assays

Lynn W. DeLeeuw, Robert C. Monsen, Vytautas Petrauskas, Robert D. Gray, Lina Baranauskiene, Daumantas Matulis, John O. Trent, Jonathan B. Chaires

published 30 Mar 2021

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DNA binding activity of the proximal C-terminal domain of rat DNA topoisomerase IIβ is involved in ICRF-193-induced closed-clamp formation

Shinji Kawano, Kunpei Fujimoto, Kazushi Yasuda, Shogo Ikeda

published 22 Sep 2020

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Dual DNA binding mode of a turn-on red fluorescent probe thiazole coumarin

Sudakshina Ganguly, Debasis Ghosh, Nagarjun Narayanaswamy, T. Govindaraju, Gautam Basu

published 17 Sep 2020

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The wing of the ToxR winged helix-turn-helix domain is required for DNA binding and activation of toxT and ompU

Sarah J. Morgan, Emily L. French, Sarah C. Plecha, Eric S. Krukonis

published 09 Sep 2019

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Substituted anthraquinones represent a potential scaffold for DNA methyltransferase 1-specific inhibitors

Rebecca L. Switzer, Jessica Medrano, David A. Reedel, Jill Weiss

published 15 Jul 2019

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Structural and catalytic insights into HoLaMa, a derivative of Klenow DNA polymerase lacking the proofreading domain

Michael Kovermann, Alessandra Stefan, Anna Castaldo, Sara Caramia, Alejandro Hochkoeppler

published 10 Apr 2019

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Functional and structural similarity of human DNA primase [4Fe4S] cluster domain constructs

Marilyn E. Holt, Lauren E. Salay, Elizabeth O’Brien, Jacqueline K. Barton, Walter J. Chazin

published 18 Dec 2018

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The monomeric form of Neisseria DNA mimic protein DMP19 prevents DNA from binding to the histone-like HU protein

Ming-Fen Huang, Shin-Jen Lin, Tzu-Ping Ko, Yi-Ting Liao, Kai-Cheng Hsu, Hao-Ching Wang

published 08 Dec 2017

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