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Dimers

Structural and functional impact of the p.R163C mutation in the conserved palindromic motif within the C-terminal domain of human αB-crystallin

Aref Baharvand, Zamara Mariam, Mohammad Bagher Shahsavani, Leila Rezaei Somee, Issa Zarei, Massoud Amanlou, Giuseppe Deganutti, Ali Akbar Saboury, Ali Akbar Moosavi-Movahedi, Reza Yousefi

published 14 Jul 2025

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Expression, purification and preliminary pharmacological characterization of the Plasmodium falciparum membrane-bound pyrophosphatase type 1

Jianing Liu, Keni Vidilaseris, Niklas G. Johansson, Orquidea Ribeiro, Loïc Dreano, Jari Yli-Kauhaluoma, Henri Xhaard, Adrian Goldman

published 27 May 2025

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Engineering of long-acting human growth hormone-Fc fusion proteins: Effects of valency, fusion position, and linker design on pharmacokinetics and efficacy

Taekyeol Lee, Dongsop Lee, Eunee Jung, Mikyung Son, Kyohwan Koo, Jaehoon Choi

published 15 May 2025

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Correlation of p53 oligomeric status and its subcellular localization in the presence of the AML-associated NPM mutant

Aleš Holoubek, Dita Strachotová, Kateřina Wolfová, Petra Otevřelova, Sára Belejová, Pavla Röselová, Aleš Benda, Barbora Brodská, Petr Herman

published 07 May 2025

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Coevolution in human small Heat Shock Protein 1 is promoted by interactions between the Alpha-Crystallin domain and the disordered regions

Vanesa Racigh, Luciana Rodriguez Sawicki, Facundo Nicolas Eric Bravo, Maria Silvina Fornasari

published 05 May 2025

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Investigating the quaternary structure of a homomultimeric catechol 1,2-dioxygenase: An integrative structural biology study

Arisbeth Guadalupe Almeida-Juarez, Shirish Chodankar, Liliana Pardo-López, Guadalupe Zavala-Padilla, Enrique Rudiño-Piñera

published 05 May 2025

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In silico studies provide new structural insights into trans-dimerization of β₁ and β₂ subunits of the Na⁺, K⁺-ATPase

Gema Ramírez-Salinas, Liora Shoshani, Jorge L. Rosas-Trigueros, Christian Sosa Huerta, Marlet Martínez-Archundia

published 29 Apr 2025

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Engineering dimer mutants of human geranylgeranyl pyrophosphate synthase

Sean J. Ezekiel, Mackenzie Searle, Jaeok Park

published 15 Jan 2025

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Biophysical and biochemical evidence for the role of acetate kinases (AckAs) in an acetogenic pathway in pathogenic spirochetes

Ranjit K. Deka, Shih-Chia Tso, Wei Z. Liu, Chad A. Brautigam

published 09 Jan 2025

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HNL Dimer in plasma is a unique and useful biomarker for the monitoring of antibiotic treatment in sepsis

Per Venge, Christer Peterson, Shengyuan Xu, Anders Larsson, Joakim Johansson, Jonas Tydén

published 26 Sep 2024

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Feasibility of the inhibitor development for cancer: A systematic approach for drug design

Yu Jiang, Ling Liu, Yichao Geng, Qingsong Li, Daxian Luo, Li Liang, Wei Liu, Weiwei Ouyang, Jianping Hu

published 22 Aug 2024

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Effect of edaphoclimate on the resin glycoside profile of the ruderal Ipomoea parasitica (Convolvulaceae)

Edmi Pérez-Sanvicente, Ismael León-Rivera, Alexandre T. Cardoso-Taketa, Irene de la C. Perea-Arango, Patricia Mussali-Galante, Susana Valencia-Díaz

published 08 Aug 2024

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Analysis of aggregation profile of glucagon using SEC-HPLC and FFF-MALS methods

Zhongli Bao, Ya-Chi Cheng, Mary Ziping Luo, Jack Yongfeng Zhang

published 21 May 2024

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