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Denaturation

A denaturation-free protocol for in situ visualization of short nuclear DNA sequences using padlock probes with rolling-circle amplification

Ryoyo Ikebuchi, Lu Xi, Dimitra Bouri, Valeriia Svintytska, Hanna Davies, Pawel Olszewski, Bozena Bruhn-Olszewska, Jan P. Dumanski, Ulf Landegren

published 28 Oct 2025

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HPV testing in cervical cancer formalin-fixed paraffin embedded tissues: Reliability of the Xpert HPV test and high-risk HPV genotypes distribution in Tunisia

Yasmine Ben Taher, Mariem Ben Rekaya, Emna Romdhane, Baligh Miladi, Linda Bel Hadj Kacem, Ahmed Med H’mayada, Nadia Ben Mansour, Farah Sassi, Emna Chelbi, Monia Tangour, Ahlem Blel, Soumaya Rammeh

published 24 Oct 2025

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Virulence gene profile and antimicrobial resistance patterns of Aeromonas hydrophila in farmed catfishes (Heteropneustes fossilis and Pangasianodon hypophthalmus) for the first time in Bangladesh

Farjana Ferdousi, Bushra Benta Rahman Prapti, Alamgir Hasan, Aminur Rahman, Ravi Yadav, Md. Shafiqul Islam, Md. Taohidul Islam, Md. Alimul Islam, Mahbubul Pratik Siddique

published 12 Sep 2025

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The type III secretion system translocases IpaC, SipC, and BipC are partially folded alpha helical proteins lacking in tertiary structures

Jacob M. Kroh, Amritangshu Chakravarty, Supratim Dey, Roberto N. De Guzman

published 12 Sep 2025

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Effects of Ionizing Radiation on the Biophysical Properties of Type I Collagen Fibrils

Kester Ng, Nader Allam, Mehrnoosh Neshatian, Mina Vaez, Liisa M. Hirvonen, Ernest Lam, Alex Vitkin, Laurent Bozec

published 02 Apr 2025

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Sweet enhancers of polymerase chain reaction

Binghua Xie, Jia Chen, Zhounan Wang, Qiao Yin, Zhong-Min Dai

published 29 Oct 2024

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Enhanced thermal stability enables human mismatch-specific thymine–DNA glycosylase to catalyse futile DNA repair

Diana Manapkyzy, Botagoz Joldybayeva, Alexander A. Ishchenko, Bakhyt T. Matkarimov, Dmitry O. Zharkov, Sabira Taipakova, Murat K. Saparbaev

published 18 Oct 2024

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May DNA analyses be biased by hidden oxidative damage? Voltammetric study of temperature and oxidation stress effect

Oskar Szczepaniak, Marta Ligaj

published 14 Jun 2024

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Using camera-guided electrode microdrive navigation for precise 3D targeting of macaque brain sites

Max Arwed Crayen, Igor Kagan, Moein Esghaei, Dirk Hoehl, Uwe Thomas, Robert Prückl, Stefan Schaffelhofer, Stefan Treue

published 28 May 2024

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Formamide denaturation of double-stranded DNA for fluorescence in situ hybridization (FISH) distorts nanoscale chromatin structure

Anne R. Shim, Jane Frederick, Emily M. Pujadas, Tiffany Kuo, I. Chae Ye, Joshua A. Pritchard, Cody L. Dunton, Paola Carrillo Gonzalez, Nicolas Acosta, Surbhi Jain, Nicholas M. Anthony, Luay M. Almassalha, Igal Szleifer, Vadim Backman

published 28 May 2024

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Discovery of allosteric regulators with clinical potential to stabilize alpha-L-iduronidase in mucopolysaccharidosis type I

Elena Cubero, Ana Ruano, Aida Delgado, Xavier Barril, Sara Morales, Ana Trapero, Lorenzo Leoni, Manolo Bellotto, Roberto Maj, Beatriz Calvo-Flores Guzmán, Natalia Pérez-Carmona, Ana Maria Garcia-Collazo

published 20 May 2024

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Biophysical characterization of the CXC chemokine receptor 2 ligands

Patrick Martin, Emily A. Kurth, David Budean, Nathalie Momplaisir, Elaine Qu, Jennifer M. Simien, Grace E. Orellana, Chad A. Brautigam, Alan V. Smrcka, Ellinor Haglund

published 16 Apr 2024

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Antibody desolvation with sodium chloride and acetonitrile generates bioactive protein nanoparticles

Levi Collin Nelemans, Vinicio Alejandro Melo, Matej Buzgo, Edwin Bremer, Aiva Simaite

published 14 Mar 2024

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