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Cytotoxic T cells

The PD-1 and CD28 molecules on T cells in peripheral blood are associated with the prognosis of patients with advanced breast cancer receiving paclitaxel chemotherapy

Ji Yang, Shuxian Qu, Xinhui Qi, Yongming Liu, Jianing Qiu, Ying Yu, Yino Wang, Zhendong Zheng, Huiying Yu

published 06 Apr 2026

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Glucocorticoids suppress early lung inflammation and impair control of SARS-CoV-2 in non-human primates

Christine E. Nelson, Keith D. Kauffman, Shunsuke Sakai, Taylor Newbolt, Jay Buchanan, Taylor W. Foreman, April M. Walker, Felipe Gomez, Joel D. Fleegle, Tuberculosis Imaging Program , Richard Herbert, Tom Hill, Sevilay Turan, Katrin D. Mayer-Barber, Reed F. Johnson, Laura E. Via, Daniel L. Barber

published 10 Mar 2026

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Spontaneous cervical artery dissection is associated with a distinct peripheral immune cell signature

Carolin Beuker, Andreas Schulte-Mecklenbeck, Timo Wirth, Ilka Kleffner, Christian Thomas, Daniel Strunk, Antje Schmidt-Pogoda, Catharina C. Gross, Luisa Klotz, Jens Minnerup

published 22 Jan 2026

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TDP2 drives immune evasion and metastatic progression in prostate cancer

Huan Cao, Anyin Pan, Yuetao Chen, Fei Zheng

published 02 Jan 2026

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Decoding the distinct immune landscape and possible regulatory mechanisms of autoimmune hepatitis through integrated single-cell and bulk RNA sequencing

Gang Chi, Yijia Che, Jinhong Pei, Xueqing Li, Junmei Wang

published 04 Dec 2025

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Single-cell transcriptomics profiling reveals cellular origins and molecular drivers underlying melanoma brain metastasis

Jingxin Zeng, Ling Lin, Yangyang Ma, Wenzhe Huang, Quan Luo, Ju Wen

published 24 Nov 2025

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β2-integrins as biomarkers in urothelial cancer

Marc Llort Asens, Imran Khan, Susanna Carola Fagerholm

published 24 Oct 2025

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Developing and experimentally validating a glucocorticoid signaling-related gene signature to evaluate the prognosis and immunotherapeutic response in kidney renal clear cell carcinoma

Yu Zhang, Chen Chen, Tianhang Zhu, Wei Luo, Ranran Zhou, Wanlong Tan

published 13 Oct 2025

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Parental influence on brown trout offspring immune cell composition: An infection study with Tetracapsuloides bryosalmonae

Helena Saura Martinez, Gary Delalay, Stephanie Talker, Heike Schmidt-Posthaus

published 24 Sep 2025

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Exploratory trajectory inference reveals convergent lineages for CD8 T cells in chronic LCMV infection

Jan T. Schleicher, Revant Gupta, Dario Cerletti, Ioana Sandu, Annette Oxenius, Manfred Claassen

published 19 Sep 2025

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Targeting the Exon2 splice cis-element in PD-1 and its effects on lymphocyte function

Yuto Tan, Naoko Kumagai-Takei, Yurika Shimizu, Akira Yamasaki, Mari Hara-Yamamoto, Shigeru Mitani, Tatsuo Ito

published 08 Sep 2025

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Low-dose aspirin is not effective as an adjunct treatment for HIV infection among people living with HIV on dolutegravir-based antiretroviral therapy: A randomised double-blind, parallel-group placebo-controlled trial

Tosi M. Mwakyandile, Grace A. Shayo, Philip G. Sasi, Peter P. Kunambi, Ferdinand M. Mugusi, Godfrey Barabona, Takamasa Ueno, Eligius F. Lyamuya

published 29 Aug 2025

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HIV-1 controllers possess a unique CD8⁺ T cell activation phenotype and loss of control is associated with increased expression of exhaustion markers

Amber D. Jones, Zachary Capriotti, Erin Santos, Angel Lin, Rachel Van Duyne, Stephen Smith, Zachary Klase

published 28 Aug 2025

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