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Cytokine therapy

Computational modeling-directed combination treatment with etanercept and mifepristone mitigates neuroinflammation in a mouse model of Gulf War Illness

Kimberly A. Kelly, Christopher M. Felton, Brenda K. Billig, Ali A. Yilmaz, James P. O’Callaghan, Travis J. A. Craddock, Gordon Broderick, Nancy Klimas, Lindsay T. Michalovicz

published 17 Mar 2026

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Combining lenalidomide with IL-2 family of cytokines enhances activating receptor and perforin/granzyme expression in NK cells

Alexandra Calescibetta, Robert Dalton, Nicole Fortenbery, Grace Ward, Sean Christiansen, Xianghong Chen, Pingyan Cheng, Tiffany Razabdouski, Annelise J. Glode, Nhan Tu, Thu Le Trinh, Jinghong Liu, Kenneth L. Wright, Sheng Wei, Erika Adriana Eksioglu

published 12 Mar 2026

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Expression of aqueous cytokines and their correlation with retinal morphological biomarkers in nAMD patients

Jingxin Zeng, Wenwen Shang, Pengfei Ren, Xiao Ke, Yonghao Zhao, Guina Liu, Jie Liu, Fang Lu, Xiaoshuang Jiang

published 11 Feb 2026

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Pulmonary fibroblasts activated by the addition of TNF-α and IL-4 enhance lymphangiogenic capacity and ameliorate lung fibrosis in an allogeneic rat model

Yuimi Matsuoka, Yuuki Shimizu, Koji Sakamoto, Makoto Matsuyama, Toyoaki Murohara, Takahiro Iwamiya

published 10 Feb 2026

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Clinical proof of concept for small molecule mediated inhibition of IL-17 in psoriasis

Richard B. Warren, Hamish J. A. Hunter, Kim A. Papp, Kenneth B. Gordon, Meina T. Tang, Jeffrey V. Enejosa, Kuan-Chieh Huang, Debasish Raha, Hashini M. Batugedara, Craig Skinner, Philip A. Kobel, Peter M. Rademacher, Nico Ghilardi, Paul Fatheree, John R. Jacobsen, Timothy T. Lu

published 23 Jan 2026

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Effects of intermittent hypoxia on adipose-derived mesenchymal stem cells in protecting alveolar type II cells from injury

RuiYin Lai, SuHeng Chen, JunJie Cui, XiaoLong Liu, YuLan Li

published 21 Jan 2026

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Dynamical modeling of TNF-α, IL-6, and IL-10 interactions in stroke-induced inflammation

Fozia Ali M. Arishi, Azmin Sham Rambely, Fatimah Abdul Razak

published 20 Jan 2026

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A TGFB2/TNF-induced in vitro model of proliferative vitreoretinopathy (PVR) using ARPE-19 cells confirms nicotinamide as an inhibitor of EMT and VEGFA secretion

Yuqing Huang, Roland Meister, Migle Lindziute, Maximilian Binter, Jan Tode, Carsten Framme, Heiko Fuchs

published 13 Jan 2026

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Lactiplantibacillus plantarum Membrane Vesicles (MVs) exhibit immunomodulatory and bactericidal effects against Escherichia coli and Salmonella Typhimurium

Cristal Dafne Lonngi Sosa, Francisco Rodolfo González Díaz, Hugo Ramírez Álvarez, Alejandro Vargas Ruíz, José Luis Muciño Hernández, Rosa Isabel Higuera Piedrahita, Héctor Alejandro de la Cruz Cruz, Marisela Leal Hernández, Gerardo Ramírez-Rico, Jorge Alfredo Cuéllar Ordaz, Cynthia González Ruíz

published 07 Jan 2026

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Disruption of epidermal growth factor receptor signaling and cytoskeletal dynamics by mebendazole and gefitinib synergistically impairs paracrine cytokine signaling in non-small cell lung cancer and triple-negative breast cancer Cell lines

Mohamed El-Tanani, Shakta Mani Satyam, Syed Arman Rabbani, Yahia El-Tanani, Mark Sutherland, Frezah Muhana

published 16 Dec 2025

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Mapping the experiences of adult cancer patients receiving chimeric antigen receptor T-cell (CAR-T) therapy: A scoping review protocol

Isabela Girleanu, Anne-Marie Brady, Vanessa Boland

published 05 Dec 2025

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The effect of therapeutic potential and safety of bone marrow-derived against adipose-derived mesenchymal stem cells in aged mice associated with septic arthritis

Alani Mohanad Khalid Ahmed, Mujahid Khalaf Ali, Basma Kh. Alani

published 26 Nov 2025

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Luteolin alleviates CUMS-induced depressive-like behavioral deficits in mice through blocking the JAK2/STAT3 pathway

Hai-hong Wu, Shang-yue Chen, Dong-liang Yuan, Ting Zhao

published 24 Oct 2025

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