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Cystic fibrosis

A physiologically-based model of localized mucociliary clearance in the airways

Monica E. Shapiro, Timothy E. Corcoran, Carol A. Bertrand, Robert S. Parker

published 14 Nov 2025

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Dysglycemia and the airway microbiome in cystic fibrosis

Laura N. Brenner, Ching-Ying Huang, Minsik Kim, Lindsay Bringhurst, Christopher J. Richards, Leonard Sicilian, Isabel Neuringer, Melissa S. Putman, Peggy S. Lai

published 07 Oct 2025

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Alternative splicing and residual function potentially expand the therapeutic landscape of the CFTRdele2ins182 variant

Cristina Pastorino, Ludovica Menta, Emanuela Pesce, Mariateresa Lena, Valeria Tomati, Valeria Capurro, Marco Di Duca, Vito Terlizzi, Andrea Gramegna, Francesco Blasi, Carlo Castellani, Serena Cappato, Federico Zara, Nicoletta Pedemonte, Renata Bocciardi

published 16 Sep 2025

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Effect of cystic fibrosis transmembrane conductance regulator modulators and dedicated cystic fibrosis gastrointestinal clinic visits on the incidence of distal intestinal obstructive syndrome in persons with cystic fibrosis

Nicha Wongjarupong, Malique F. Delbrune, Jameel Alp, Daphne M. Moutsoglou, Talia Wiggen, Ashley Benner, Joanne L. Billings, Jordan M. Dunitz, Sarah J. Schwarzenberg, Baharak Moshiree, Shahnaz Sultan

published 28 Jul 2025

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Understanding the action of bamocaftor as a potential drug candidate against Cystic Fibrosis Transmembrane Regulator protein: A computational approach

Naisarg Patel, Samrat Sarkar, Bala Murali V M, Ishan Kashyap, Premkumar Thiruselvam, Vino Sundararajan, Sajitha Lulu Sudhakaran

published 23 Jul 2025

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Thoracic magnetic resonance imaging in non-tuberculous mycobacterial pulmonary disease: Characteristics and potential implementation

Ieuan Edward Shepherd Evans, Timothy Baird, Charles S. Haworth, Christopher Johnson, Helen Barker, Uta Hill, Dorothy Grogono, Odiri Eneje, Nicholas Screaton, Andres Floto

published 23 Jun 2025

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The differential burden of acute rhinovirus infections in children with underlying conditions

María Isabel Sánchez Códez, Isabel Benavente Fernández, Katherine Moyer, Amy L. Leber, Octavio Ramilo, Asuncion Mejias

published 14 May 2025

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Arsenic exposure is associated with elevated sweat chloride concentration and airflow obstruction among adults in Bangladesh: A cross-sectional study

Mi-Sun S. Lee, Crystal M. North, Irada Choudhuri, Subrata K. Biswas, Abby F. Fleisch, Afifah Farooque, Diane Bao, Sakila Afroz, Sadia Mow, Nazmul Husain, Fuadul Islam, Md Golam Mostofa, Partha Pratim Biswas, David S. Ludwig, Subba R. Digumarthy, Christopher Hug, Quazi Quamruzzaman, David C. Christiani, Maitreyi Mazumdar

published 07 May 2025

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Roscovitine enhances the bactericidal activity of the airway surface liquid of the cystic fibrosis bronchial epithelium but does not protect against Pseudomonas aeruginosa infection

Adrien Maupas, Anaëlle Muggeo, Pierre Vermeulen, Sophie Moussalih, Edouard Sage, Emilie Luczka-Majérus, Christelle Coraux, Thomas Guillard

published 05 May 2025

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Living with cystic fibrosis during the COVID-19 pandemic: An interpretive description of healthcare access from patients with cystic fibrosis and their providers in Alberta, Canada

Katelyn Brehon, Pam Hung, Maxi Miciak, Winnie M. Leung, Kadija Perreault, Douglas P. Gross, Jason Weatherald, Paul E. Ronksley, Michael K. Stickland, Grace Y. Lam

published 02 May 2025

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Infection model of THP-1 cells, growth dynamics, and antimicrobial susceptibility of clinical Mycobacterium abscessus isolates from cystic fibrosis patients: Results from a multicentre study

Alba Ruedas-López, Marta Tato, Laura Lerma, Jaime Esteban, María-Carmen Muñoz-Egea, Carlos Toro, Diego Domingo, Rafael Prados-Rosales, Paula López-Roa

published 31 Mar 2025

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Prospective Analysis of urINe LAM to Eliminate NTM Sputum Screening (PAINLESS) study: Rationale and trial design for testing urine lipoarabinomannan as a marker of NTM lung infection in cystic fibrosis

Kara M. Calhoun, Emily Armantrout, Katie Poch, Silvia Caceres, Valerie K. Lovell, Marion Jones, Kenneth C. Malcolm, Brian Vestal, Emily Wheeler, Noel Rysavy, Jordan Manzer, Ibrahim Aboellail, Delphi Chatterjee, Jerry A. Nick

published 10 Mar 2025

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Proof of concept pilot study to assess the utility of magnetic resonance extra-cellular volume quantification to diagnose advanced liver disease in people with Cystic Fibrosis

Daniel H. Tewkesbury, Jennifer A. Scott, Rowland J. Bright-Thomas, Sue Liong, Josephine Naish, Velauthan Rudralingam, Karen Piper Hanley, Andrew M. Jones, Varinder S. Athwal

published 04 Mar 2025

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