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Cyclins

Nano-curcumin enhances the sensitivity of tamoxifen-resistant breast cancer cells via the Cyclin D1-DILA1 axis and the PI3K/AKT/mTOR pathway downregulation

Taraneh Givi, Fatemeh Mohajerani, Zahra Moazezi Tehrankhah, Mohammadjavad Karimi Taheri, Maryam Amirahmadi, Sadegh Babashah, Majid Sadeghizadeh

published 05 Dec 2025

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Targeting the cyclin D/CDK4 Axis to unlock new therapeutic approaches to enhance cancer treatment

Ibrahim Khater, Aaya Nassar

published 22 Aug 2025

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The Hippo-YAP/β-catenin signaling axis coordinates odontogenic differentiation in dental pulp stem cells: Implications for dentin-pulp regeneration

Chang Chen, Qiqi Yun, Juanli Ran, Ziyao Zhou, Pengxiang Zhang, Rong Li

published 26 Jun 2025

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Thymoquinone loaded on chitosan nanoparticles alleviated the consequences of cryptosporidiosis infection in a murine model: Evidence from parasitological, histopathological, immunohistochemical, and immunological studies

Abdelmoneim A. Ali, Eman S. El-Wakil, Al-sayed R. Al-Attar, Mahmoud Fawzy, Aya Samy, Zienab E. Eldin, Wafa Abdullah I. Al-Megrin, John T. Nazeer

published 30 May 2025

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Exosomes from human umbilical cord mesenchymal stem cells promote the growth of human hair dermal papilla cells

Yu-Cheng Chen, Wei-Cheng Tsai, Zhi-Xiang Li, Wan-Jung Lin, Hao-Yu Lin, Yi-Ju Hsieh, Kai-Hsuan Wang, You-Yan Chen, Tsong-Long Hwang, Tzou-Yien Lin

published 30 Apr 2025

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The RNA-binding protein Puf5 and the HMGB protein Ixr1 regulate cell cycle-specific expression of CLB1 and CLB2 in Saccharomyces cerevisiae

Megumi Sato, Varsha Rana, Yasuyuki Suda, Tomoaki Mizuno, Kenji Irie

published 03 Feb 2025

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Inotodiol induces hepatocellular carcinoma apoptosis by activation of MAPK/ERK pathway

Yushuang Xing, Di Jia, Xinping Zhu, Jialu Yang, Zhipeng Gao, Nana Meng, Haohao Xu, Mengxiao Wang, Shijun Chang, Mingqian Zhao, Shanbo Zhang, Zichen Mu, Qiang Tang, Weiming Zhao

published 29 Jan 2025

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Cyclosporine A causes gingival overgrowth via reduced G₁ cell cycle arrest in gingival fibroblasts

Reiri Takeuchi, Takatoshi Nomura, Manabu Yaguchi, Noriko Kuwahara, Yuta Amino, Chieko Taguchi, Itaru Suzuki, Haruka Suzuki, Teruaki Nagashima, Kazumune Arikawa, Yuichiro Okada, Takato Nomoto, Koichi Hiratsuka

published 20 Dec 2024

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Curating models from BioModels: Developing a workflow for creating OMEX files

Jin Xu, Lucian Smith

published 05 Dec 2024

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Current evidence and future direction on evaluating the anticancer effects of curcumin, gingerols, and shogaols in cervical cancer: A systematic review

Unwaniah Abdull Rahim, Marami Mustapa, Nik Noorul Shakira Mohamed Shakrin, Armania Nurdin, Nursiati Mohamad Taridi, Yasmin Anum Mohd Yusof, Mariam Firdhaus Mad Nordin, Nur Aishah Che Roos

published 22 Nov 2024

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Camellia sinensis methanolic leaves extract: Phytochemical analysis and anticancer activity against human liver cancer cells

Demiana H. Hanna, Ahlam K. Al-Atmani, Aljazi Abdullah AlRashidi, E. El. Shafee

published 14 Nov 2024

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Molecular mechanism of ectopic lipid accumulation induced by methylglyoxal via activation of the NRF2/PI3K/AKT pathway implicates renal lipotoxicity caused by diabetes mellitus

Chiung Chi Peng, Eugene Chang Yu Chen, Chang-Rong Chen, Charng-Cherng Chyau, Kuan-Chou Chen, Robert Y. Peng

published 16 Oct 2024

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The role of cornulin (CRNN) in the progression of cutaneous squamous cell carcinoma involving AKT activation in SCL-1

Changji Li, Peiwen Yang, Xin Wang, Hongbao Li, Huiling Jing, Yan Zheng, Yuzhu Hou

published 18 Sep 2024

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