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COX-2 inhibitors

A randomised pilot trial of perioperative propranolol combined with celecoxib versus standard of care in stage III melanoma: The ProCel study protocol

Katina J. Selvaraj, Diona L. Damian, J. Guy Lyons, James S. Wilmott, Peter M. Ferguson, Michele McGrady, Iris Bartula, Serigne N. Lo, Richard A. Scolyer, Angela L. Ferguson, Robyn P.M. Saw

published 29 Jan 2026

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Umbilical cord mesenchymal stem cell exosomal miR-143-3p delays endothelial cell senescence through targeting COX-2

Zhi-peng Yang, Shui-hong Lu, Yan-hong Pan, Zhao-fu Liao, Yi-tuan Xie, Heng Li, Yu-lan Zhou, Zhen-can Shi, Yun-fei Qu, Zhu-guo Wu, Chongxiang Xiong, Xing-dong Xiong

published 11 Jul 2025

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Carbonic anhydrase IX downregulation linked to disruption of HIF-1, NFκB and STAT3 pathways as a new mechanism of ibuprofen anti-cancer effect

Katarina Grossmannova, Petra Belvoncikova, Barbora Puzderova, Veronika Simko, Lucia Csaderova, Jaromir Pastorek, Monika Barathova

published 23 May 2025

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Pharmacological and behavioral investigation of putative self-medicative plants in Budongo chimpanzee diets

Elodie Freymann, Susana Carvalho, Leif A. Garbe, Dinda Dwi Ghazhelia, Catherine Hobaiter, Michael A. Huffman, Geresomu Muhumuza, Lena Schulz, Daniel Sempebwa, Florian Wald, Eguma R. Yikii, Klaus Zuberbühler, Fabien Schultz

published 20 Jun 2024

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Papain ameliorates monocyte-platelet aggregate formation-mediated inflammatory responses in monocytes by upregulating miRNA-146a transcription

Lei Jiang, Chan Xu, Yan Zhao, Qinghua Huang, Wufeng Yuan, Yan Wu, Xianming Fei

published 21 Nov 2022

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Pellucidin A promotes antinociceptive activity by peripheral mechanisms inhibiting COX-2 and NOS: In vivo and in silico study

Amanda Pâmela Santos Queiroz, Manolo Cleiton Costa Freitas, José Rogério A. Silva, Anderson Bentes Lima, Leila Sawada, Rayan Fidel Martins Monteiro, Ana Carolina Gomes Albuquerque de Freitas, Luís Antônio Loureiro Maués, Alberto Cardoso Arruda, Milton Nascimento Silva, Cristiane Socorro Ferraz Maia, Enéas Andrade Fontes-Júnior, José Luiz M. do Nascimento, Mara Silvia P. Arruda, Gilmara N. T. Bastos

published 17 Sep 2020

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Nonsteroidal anti-inflammatory drugs and acetaminophen ameliorate muscular mechanical hyperalgesia developed after lengthening contractions via cyclooxygenase-2 independent mechanisms in rats

Tetsuhiro Shimodaira, Shigeo Mikoshiba, Toru Taguchi

published 06 Nov 2019

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Celecoxib enhances the sensitivity of non-small-cell lung cancer cells to radiation-induced apoptosis through downregulation of the Akt/mTOR signaling pathway and COX-2 expression

Pan Zhang, Dan He, Erqun Song, Mingdong Jiang, Yang Song

published 15 Oct 2019

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Trends in polypharmacy and dispensed drugs among adults in the Netherlands as compared to the United States

Monika P. Oktora, Petra Denig, Jens H. J. Bos, Catharina C. M. Schuiling-Veninga, Eelko Hak

published 22 Mar 2019

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Generating and evaluating a propensity model using textual features from electronic medical records

Zubair Afzal, Gwen M. C. Masclee, Miriam C. J. M. Sturkenboom, Jan A. Kors, Martijn J. Schuemie

published 04 Mar 2019

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Cigarette smoke extracts and cadmium induce COX-2 expression through γ-secretase-mediated p38 MAPK activation in C6 astroglia cells

Hyun Joung Lim, Jung Hyun Park, Chulman Jo, Keejung Yoon, Young Ho Koh

published 22 Feb 2019

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Impact of a selective cyclooxygenase-2 inhibitor, celecoxib, on cortical excitability and electrophysiological properties of the brain in healthy volunteers: A randomized, double-blind, placebo-controlled study

Jung-Ah Lim, Ki-Young Jung, Boram Park, Tae-Joon Kim, Jin-Sun Jun, Keun Tae Kim, Tae-Won Yang, Soon-Tae Lee, Keun-Hwa Jung, Kon Chu, Sang Kun Lee, Kyung-Il Park

published 22 Feb 2019

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NF-κB p65 and p105 implicate in interleukin 1β-mediated COX-2 expression in melanoma cells

Nanako Kitanaka, Rei Nakano, Taku Kitanaka, Shinichi Namba, Tadayoshi Konno, Tomohiro Nakayama, Hiroshi Sugiya

published 18 Dec 2018

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