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Complement inhibitors

Upregulation of Glycolytic Enzymes, Mitochondrial Dysfunction and Increased Cytotoxicity in Glial Cells Treated with Alzheimer’s Disease Plasma

Tharusha Jayasena, Anne Poljak, Nady Braidy, George Smythe, Mark Raftery, Mark Hill, Henry Brodaty, Julian Trollor, Nicole Kochan, Perminder Sachdev

published 18 Mar 2015

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Different IVIG Glycoforms Affect In Vitro Inhibition of Anti-Ganglioside Antibody-Mediated Complement Deposition

Makoto Sudo, Yoshiki Yamaguchi, Peter J. Späth, Kana Matsumoto-Morita, Benjamin K. Ong, Nortina Shahrizaila, Nobuhiro Yuki

published 26 Sep 2014

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c-Src Binds to the Cancer Drug Ruxolitinib with an Active Conformation

Yankun Duan, Lin Chen, Yongheng Chen, Xue-gong Fan

published 08 Sep 2014

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Potential Therapeutic Benefit of C1-Esterase Inhibitor in Neuromyelitis Optica Evaluated In Vitro and in an Experimental Rat Model

Lukmanee Tradtrantip, Nithi Asavapanumas, Puay-Wah Phuan, A. S. Verkman

published 05 Sep 2014

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Inhibition of C3 Convertase Activity by Hepatitis C Virus as an Additional Lesion in the Regulation of Complement Components

Hangeun Kim, Keith Meyer, Adrian M. Di Bisceglie, Ranjit Ray

published 01 Jul 2014

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A Novel Antibody against Human Properdin Inhibits the Alternative Complement System and Specifically Detects Properdin from Blood Samples

Diana Pauly, Benedikt M. Nagel, Jörg Reinders, Tobias Killian, Matthias Wulf, Susanne Ackermann, Boris Ehrenstein, Peter F. Zipfel, Christine Skerka, Bernhard H. F. Weber

published 05 May 2014

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Exopolysaccharides Isolated from Hydrothermal Vent Bacteria Can Modulate the Complement System

Anthony Courtois, Christian Berthou, Jean Guézennec, Claire Boisset, Anne Bordron

published 15 Apr 2014

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Hepatitis C Virus NS3/4A Protease Inhibits Complement Activation by Cleaving Complement Component 4

Seiichi Mawatari, Hirofumi Uto, Akio Ido, Kenji Nakashima, Tetsuro Suzuki, Shuji Kanmura, Kotaro Kumagai, Kohei Oda, Kazuaki Tabu, Tsutomu Tamai, Akihiro Moriuchi, Makoto Oketani, Yuko Shimada, Masayuki Sudoh, Ikuo Shoji, Hirohito Tsubouchi

published 12 Dec 2013

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Human Factor H-Related Protein 2 (CFHR2) Regulates Complement Activation

Hannes U. Eberhardt, Denise Buhlmann, Peter Hortschansky, Qian Chen, Sascha Böhm, Markus J. Kemper, Reinhard Wallich, Andrea Hartmann, Teresia Hallström, Peter F. Zipfel, Christine Skerka

published 18 Nov 2013

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Different Host Complement Systems and Their Interactions with Saliva from Lutzomyia longipalpis (Diptera, Psychodidae) and Leishmania infantum Promastigotes

Antonio Ferreira Mendes-Sousa, Alexandre Alves Sousa Nascimento, Daniel Costa Queiroz, Vladimir Fazito Vale, Ricardo Toshio Fujiwara, Ricardo Nascimento Araújo, Marcos Horácio Pereira, Nelder Figueiredo Gontijo

published 08 Nov 2013

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Topical Application of PPADS Inhibits Complement Activation and Choroidal Neovascularization in a Model of Age-Related Macular Degeneration

Kerstin Birke, Erion Lipo, Marco T. Birke, Rajendra Kumar-Singh

published 09 Oct 2013

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Brown Recluse Spider Bite Mediated Hemolysis: Clinical Features, a Possible Role for Complement Inhibitor Therapy, and Reduced RBC Surface Glycophorin A as a Potential Biomarker of Venom Exposure

Eric A. Gehrie, Hui Nian, Pampee P. Young

published 27 Sep 2013

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Fast Docking on Graphics Processing Units via Ray-Casting

Karen R. Khar, Lukasz Goldschmidt, John Karanicolas

published 16 Aug 2013

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