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Complement inhibitors

Complement and the Alternative Pathway Play an Important Role in LPS/D-GalN-Induced Fulminant Hepatic Failure

Shihui Sun, Yan Guo, [ ... ], Yusen Zhou

Upregulation of Glycolytic Enzymes, Mitochondrial Dysfunction and Increased Cytotoxicity in Glial Cells Treated with Alzheimer’s Disease Plasma

Tharusha Jayasena, Anne Poljak, [ ... ], Perminder Sachdev

What Does It Take to Synergistically Combine Sub-Potent Natural Products into Drug-Level Potent Combinations?

Chu Qin, Kai Leng Tan, [ ... ], Yu Yang Jiang

c-Src Binds to the Cancer Drug Ruxolitinib with an Active Conformation

Yankun Duan, Lin Chen, Yongheng Chen, Xue-gong Fan

Human Factor H-Related Protein 2 (CFHR2) Regulates Complement Activation

Hannes U. Eberhardt, Denise Buhlmann, [ ... ], Christine Skerka

The Role of Salivary and Intestinal Complement System Inhibitors in the Midgut Protection of Triatomines and Mosquitoes

Veruska Cavalcanti Barros, Jéssica Góes Assumpção, [ ... ], Nelder Figueiredo Gontijo

Variability and Action Mechanism of a Family of Anticomplement Proteins in Ixodes ricinus

Bernard Couvreur, Jérôme Beaufays, [ ... ], Edmond Godfroid

A computational model for the evaluation of complement system regulation under homeostasis, disease, and drug intervention

Nehemiah Zewde, Dimitrios Morikis

Pharmacokinetics and pharmacodynamics of pozelimab alone or in combination with cemdisiran in non-human primates

Kishor Devalaraja-Narashimha, Cong Huang, [ ... ], Marc W. Retter

Peptide Inhibitor of Complement C1 (PIC1) Rapidly Inhibits Complement Activation after Intravascular Injection in Rats

Julia A. Sharp, Pamela S. Hair, [ ... ], Neel K. Krishna

Human Tamm-Horsfall protein, a renal specific protein, serves as a cofactor in complement 3b degradation

Diana C. J. Rhodes

Fast Docking on Graphics Processing Units via Ray-Casting

Karen R. Khar, Lukasz Goldschmidt, John Karanicolas

Algorithmic Modeling Quantifies the Complementary Contribution of Metabolic Inhibitions to Gemcitabine Efficacy

Ozan Kahramanoğullari, Gianluca Fantaccini, [ ... ], Corrado Priami

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