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Complement inhibitors

Genetic strategy to decrease complement activation with adenoviral therapies

Christopher M. Gentile, Anton V. Borovjagin, [ ... ], Jason M. Warram

Absence of pathogenic mutations in CD59 in chronic inflammatory demyelinating polyradiculoneuropathy

Lena Duchateau, Lorena Martín-Aguilar, [ ... ], Luis Querol

Complement inhibition ameliorates blast-induced acute lung injury in rats: Potential role of complement in intracellular HMGB1-mediated inflammation

Yansong Li, Zhangsheng Yang, [ ... ], Leopoldo C. Cancio

A computational model for the evaluation of complement system regulation under homeostasis, disease, and drug intervention

Nehemiah Zewde, Dimitrios Morikis

Design and preclinical characterization of ALXN1210: A novel anti-C5 antibody with extended duration of action

Douglas Sheridan, Zhao-Xue Yu, [ ... ], Paul Tamburini

The use of the vaccinia virus complement control protein (VCP) in the rat retina

Nilisha Fernando, Riccardo Natoli, [ ... ], Krisztina Valter

Peptide Inhibitor of Complement C1 (PIC1) demonstrates antioxidant activity via single electron transport (SET) and hydrogen atom transfer (HAT)

Magdielis Gregory Rivera, Pamela S. Hair, Kenji M. Cunnion, Neel K. Krishna

MASP-1 of the complement system enhances clot formation in a microvascular whole blood flow model

Lorenz Jenny, József Dobó, [ ... ], Verena Schroeder

Human Tamm-Horsfall protein, a renal specific protein, serves as a cofactor in complement 3b degradation

Diana C. J. Rhodes

Inhibition of Myeloperoxidase Activity in Cystic Fibrosis Sputum by Peptide Inhibitor of Complement C1 (PIC1)

Pamela S. Hair, Laura A. Sass, Neel K. Krishna, Kenji M. Cunnion

Complement Activation and STAT4 Expression Are Associated with Early Inflammation in Diabetic Wounds

Kenji M. Cunnion, Neel K. Krishna, [ ... ], Anca D. Dobrian

Differential Expression of Complement Markers in Normal and AMD Transmitochondrial Cybrids

Sonali Nashine, Marilyn Chwa, [ ... ], M. Cristina Kenney

Quantitative Modeling of the Alternative Pathway of the Complement System

Nehemiah Zewde, Ronald D. Gorham Jr., Angel Dorado, Dimitrios Morikis

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