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Complement inhibitors

Design and preclinical characterization of ALXN1210: A novel anti-C5 antibody with extended duration of action

Douglas Sheridan, Zhao-Xue Yu, [ ... ], Paul Tamburini

The use of the vaccinia virus complement control protein (VCP) in the rat retina

Nilisha Fernando, Riccardo Natoli, [ ... ], Krisztina Valter

Peptide Inhibitor of Complement C1 (PIC1) demonstrates antioxidant activity via single electron transport (SET) and hydrogen atom transfer (HAT)

Magdielis Gregory Rivera, Pamela S. Hair, Kenji M. Cunnion, Neel K. Krishna

MASP-1 of the complement system enhances clot formation in a microvascular whole blood flow model

Lorenz Jenny, József Dobó, [ ... ], Verena Schroeder

Human Tamm-Horsfall protein, a renal specific protein, serves as a cofactor in complement 3b degradation

Diana C. J. Rhodes

Inhibition of Myeloperoxidase Activity in Cystic Fibrosis Sputum by Peptide Inhibitor of Complement C1 (PIC1)

Pamela S. Hair, Laura A. Sass, Neel K. Krishna, Kenji M. Cunnion

Complement Activation and STAT4 Expression Are Associated with Early Inflammation in Diabetic Wounds

Kenji M. Cunnion, Neel K. Krishna, [ ... ], Anca D. Dobrian

Differential Expression of Complement Markers in Normal and AMD Transmitochondrial Cybrids

Sonali Nashine, Marilyn Chwa, [ ... ], M. Cristina Kenney

Quantitative Modeling of the Alternative Pathway of the Complement System

Nehemiah Zewde, Ronald D. Gorham Jr., Angel Dorado, Dimitrios Morikis

Impact of Reducing Complement Inhibitor Binding on the Immunogenicity of Native Neisseria meningitidis Outer Membrane Vesicles

Helene Daniels-Treffandier, Karlijn de Nie, [ ... ], Christine S. Rollier

Conserved Patterns of Microbial Immune Escape: Pathogenic Microbes of Diverse Origin Target the Human Terminal Complement Inhibitor Vitronectin via a Single Common Motif

Teresia Hallström, Birendra Singh, [ ... ], Kristian Riesbeck

Pseudomonas aeruginosa Uses Dihydrolipoamide Dehydrogenase (Lpd) to Bind to the Human Terminal Pathway Regulators Vitronectin and Clusterin to Inhibit Terminal Pathway Complement Attack

Teresia Hallström, Melanie Uhde, [ ... ], Peter F. Zipfel

Peptide Inhibitor of Complement C1 (PIC1) Rapidly Inhibits Complement Activation after Intravascular Injection in Rats

Julia A. Sharp, Pamela S. Hair, [ ... ], Neel K. Krishna

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