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Complement inhibitors

Design and preclinical characterization of ALXN1210: A novel anti-C5 antibody with extended duration of action

Douglas Sheridan, Zhao-Xue Yu, [ ... ], Paul Tamburini

Functional Analyses of Complement Convertases Using C3 and C5-Depleted Sera

Marcin Okroj, Emelie Holmquist, Ben C. King, Anna M. Blom

Quantitative Modeling of the Alternative Pathway of the Complement System

Nehemiah Zewde, Ronald D. Gorham Jr., Angel Dorado, Dimitrios Morikis

Staphylococcus aureus Surface Protein SdrE Binds Complement Regulator Factor H as an Immune Evasion Tactic

Julia A. Sharp, Charlene G. Echague, [ ... ], Kenji M. Cunnion

Complement C1 Esterase Inhibitor Levels Linked to Infections and Contaminated Heparin-Associated Adverse Events

Zhao-Hua Zhou, Trina Chen, [ ... ], Steven Kozlowski

Brown Recluse Spider Bite Mediated Hemolysis: Clinical Features, a Possible Role for Complement Inhibitor Therapy, and Reduced RBC Surface Glycophorin A as a Potential Biomarker of Venom Exposure

Eric A. Gehrie, Hui Nian, Pampee P. Young

Topical Application of PPADS Inhibits Complement Activation and Choroidal Neovascularization in a Model of Age-Related Macular Degeneration

Kerstin Birke, Erion Lipo, Marco T. Birke, Rajendra Kumar-Singh

Novel Scabies Mite Serpins Inhibit the Three Pathways of the Human Complement System

Angela Mika, Simone L. Reynolds, [ ... ], Katja Fischer

The Systemic Cytokine Environment Is Permanently Altered in Multiple Myeloma

Mary M. Zheng, Zhifang Zhang, [ ... ], Julia Kirshner

A Novel Antibody against Human Properdin Inhibits the Alternative Complement System and Specifically Detects Properdin from Blood Samples

Diana Pauly, Benedikt M. Nagel, [ ... ], Bernhard H. F. Weber

Borrelia valaisiana Resist Complement-Mediated Killing Independently of the Recruitment of Immune Regulators and Inactivation of Complement Components

Jasmin Schwab, Claudia Hammerschmidt, [ ... ], Peter Kraiczy

Contribution of Chondroitin Sulfate A to the Binding of Complement Proteins to Activated Platelets

Osama A. Hamad, Per H. Nilsson, [ ... ], Kristina Nilsson Ekdahl

Proteomic Biomarkers for Acute Interstitial Lung Disease in Gefitinib-Treated Japanese Lung Cancer Patients

Fredrik Nyberg, Atsushi Ogiwara, [ ... ], Harubumi Kato

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