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Column chromatography

5-(3,5-Dinitrophenyl)-1,3,4-oxadiazol-2-amine derivatives, their precursors, and analogues: Synthesis and evaluation of novel highly potent antitubercular agent

Václav Pflégr, Jiřina Stolaříková, Galina Karabanovich, Jana Maixnerová, Adrián Pál, Jana Korduláková, Zuzana Šanderová, Michaela Liegertová, Jaroslav Roh, František Trejtnar, Jarmila Vinšová, Martin Krátký

published 29 May 2025

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Differential gene regulation by a synthetic vitamin D receptor ligand and active vitamin D in human cells

Miho Iwaki, Yoshiaki Kanemoto, Takahiro Sawada, Koki Nojiri, Tomohiro Kurokawa, Rino Tsutsumi, Kazuo Nagasawa, Shigeaki Kato

published 13 Dec 2023

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Design and synthesis of novel anti-urease imidazothiazole derivatives with promising antibacterial activity against Helicobacter pylori

Afnan I. Shahin, Sumera Zaib, Seyed-Omar Zaraei, Reena A. Kedia, Hanan S. Anbar, Muhammad Tayyab Younas, Taleb H. Al-Tel, Ghalia Khoder, Mohammed I. El-Gamal

published 02 Jun 2023

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Pterin-based small molecule inhibitor capable of binding to the secondary pocket in the active site of ricin-toxin A chain

Ryota Saito, Masaru Goto, Shun Katakura, Taro Ohba, Rena Kawata, Kazuki Nagatsu, Shoko Higashi, Kaede Kurisu, Kaori Matsumoto, Kouta Ohtsuka

published 12 Dec 2022

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Analysis and differentiation of tobacco-derived and synthetic nicotine products: Addressing an urgent regulatory issue

Andrew G. Cheetham, Susan Plunkett, Preston Campbell, Jacob Hilldrup, Bonnie G. Coffa, Stan Gilliland III, Steve Eckard

published 14 Apr 2022

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Bioactive triterpenoids from Solanum torvum fruits with antifungal, resistance modulatory and anti-biofilm formation activities against fluconazole-resistant candida albicans strains

Benjamin Kingsley Harley, David Neglo, Philip Tawiah, Mercy Adansi Pipim, Nana Ama Mireku-Gyimah, Clement Okraku Tettey, Cedric Dzidzor Amengor, Theophilus Christian Fleischer, Sayanika Devi Waikhom

published 28 Dec 2021

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Inhibitory effects of compounds from the roots of Potentilla longifolia on lipid accumulation

Shengxi Lin, Xiaoyan Zhao, Yunpeng Sun, Huan Liu, Mingyang Shang, Jinyan Gong, Qianqian Ma, Guangchun Piao, Haidan Yuan

published 09 Sep 2020

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Discovery of novel West Nile Virus protease inhibitor based on isobenzonafuranone and triazolic derivatives of eugenol and indan-1,3-dione scaffolds

André S. de Oliveira, Poliana A. R. Gazolla, Ana Flávia C. da S. Oliveira, Wagner L. Pereira, Lívia C. de S. Viol, Angélica F. da S. Maia, Edjon G. Santos, Ítalo E. P. da Silva, Tiago A. de Oliveira Mendes, Adalberto M. da Silva, Roberto S. Dias, Cynthia C. da Silva, Marcelo D. Polêto, Róbson R. Teixeira, Sergio O. de Paula

published 26 Sep 2019

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Scaffold hopping from (5-hydroxymethyl) isophthalates to multisubstituted pyrimidines diminishes binding affinity to the C1 domain of protein kinase C

Riccardo Provenzani, Ilari Tarvainen, Giulia Brandoli, Antti Lempinen, Sanna Artes, Ainoleena Turku, Maria Helena Jäntti, Virpi Talman, Jari Yli-Kauhaluoma, Raimo K. Tuominen, Gustav Boije af Gennäs

published 11 Apr 2018

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Design and synthesis of constrained bicyclic molecules as candidate inhibitors of influenza A neuraminidase

Cinzia Colombo, Črtomir Podlipnik, Leonardo Lo Presti, Masahiro Niikura, Andrew J. Bennet, Anna Bernardi

published 28 Feb 2018

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Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38α MAPK

Mike Bührmann, Bianca M. Wiedemann, Matthias P. Müller, Julia Hardick, Maria Ecke, Daniel Rauh

published 11 Sep 2017

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Transetherification of 2,4-dimethoxynitrobenzene by aromatic nucleophilic substitution

Jiho Song, Hae Ju Kang, Jung Wuk Lee, Michelle A. Wenas, Seung Hwarn Jeong, Taeho Lee, Kyungsoo Oh, Kyung Hoon Min

published 23 Aug 2017

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Oxazin-5-Ones as a Novel Class of Penicillin Binding Protein Inhibitors: Design, Synthesis and Structure Activity Relationship

Efeturi Abraham Onoabedje, Akachukwu Ibezim, Sunday Nwankwor Okafor, Ufuoma Shalom Onoabedje, Uchechukwu Chris Okoro

published 17 Oct 2016

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